Disease relevance of Euflavine

• In a randomized, double-blind investigation 36 men undergoing sterilization had irrigation of the vas deferens with either sterile water or the spermicide, euflavine, to reduce the lag to sterility [1].
• However, one trial reported fewer median number of ejaculations to azoospermia with euflavine rather than water irrigation [2].

High impact information on Euflavine

• The CIE test was compared with the indirect hemagglutination (IHA) and acriflavine (AF) tests [3].
• However, even in the group irrigated with euflavine 6 to 35 days elapsed before the semen samples were without potentially fertile spermatozoa [1].
• Respiration-deficient mutants (Rho-, petite) of Saccharomyces carlsbergensis were obtained by treatment with trypaflavin (euflavine) [4].

Analytical, diagnostic and therapeutic context of Euflavine

• Irrigation during vasectomy: a comparison between sterile water and the spermicide euflavine [1].
• The treatment resulted in a reduced stainability of the brain with the Timm histochemical procedure for "heavy metals". In contrast, analysis by flameless atomic absorption spectrophotometry showed no significant changes in the concentrations of zinc and of copper after euflavine treatment [5].

References