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Chemical Compound Review:

Hydramycin (2Z,4S,4aR,5S,5aS,6R,12aS)-2- (amino...

Synonyms:

Ole-Mapenay, I.M. et al., Ning, S.B. et al., Ole-Mapenay, I.M. et al., Tang, S.J. et al., Xie, L.P. et al., et al.

Xie, Xin, Ning, Zhang,

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Disease relevance of Vibravenos

The clinical efficacy of doxycycline (Doxycen, Cenavisa, Spain), a long-acting preparation, was evaluated for treatment of Pasteurella haemolytica infection in 6 goats [1].
Endoscopic injection sclerotherapy with doxycycline for lymphatic and low-flow vascular malformations in the GI tract is feasible, easy, safe, and effective [2].

High impact information on Vibravenos

Dox-induced activation of the mEET gene profoundly inhibited MCP-1 expression at both mRNA and protein levels and alleviated its chemotactic activity [3].
The U2OS-ERalpha and U2OS-ERbeta cell lines were treated with Dox and either vehicle control or E2 for 24 h [4].
Cultured ESMC were coinfected by Adeno-X-TRE-eNOS and regulation virus (Adeno-X Tet-off virus), and the Dox-regulated eNOS expression was detected by RT-PCR and western blot [5].
The effect of experimentally induced Pasteurella haemolytica pneumonia on the pharmacokinetics of doxycycline (Doxycen Retard) administered intramuscularly was studied in seven East African dwarf goats [6].

References

Efficacy of doxycycline in a goat model of Pasteurella pneumonia. Ole-Mapenay, I.M., Mitema, E.S. Journal of the South African Veterinary Association. (1997) [Pubmed]
Endoscopic injection sclerotherapy with doxycycline for mediastinal and esophageal lymphangiohemangioma. Tang, S.J., Sreenarasimhaiah, J., Tang, L., Rollins, N., Purdy, P.D. Gastrointest. Endosc. (2007) [Pubmed]
Negative regulation of monocyte chemoattractant protein-1 gene expression by a mouse estrogen-enhanced transcript. Xie, L.P., Fu, W.X., Jin, C., Dong, X.Y., Chen, W.F. Eur. J. Immunol. (2002) [Pubmed]
Estrogen receptor isoform-specific regulation of endogenous gene expression in human osteoblastic cell lines expressing either ERalpha or ERbeta. Monroe, D.G., Getz, B.J., Johnsen, S.A., Riggs, B.L., Khosla, S., Spelsberg, T.C. J. Cell. Biochem. (2003) [Pubmed]
Construction of a recombinant adenovirus carrying endothelial nitric oxide synthase gene and its expression and control in esophageal smooth muscle cells. Ning, S.B., Zhang, Z.B., Xie, W.F., Xin, S.L. Chinese journal of digestive diseases. (2004) [Pubmed]
Aspects of the pharmacokinetics of doxycycline given to healthy and pneumonic East African dwarf goats by intramuscular injection. Ole-Mapenay, I.M., Mitema, E.S., Maitho, T.E. Vet. Res. Commun. (1997) [Pubmed]

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