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Chemical Compound Review

CHEMBL26138     8-[(E)-2-(3- chlorophenyl)ethenyl]- 1,3,7...

Synonyms: C197_SIGMA, SureCN1754984, CHEBI:53115, Csc cpd, CCG-204487, ...
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Disease relevance of Csc cpd


High impact information on Csc cpd


Biological context of Csc cpd

  • Subsequently, the deduced binding site was used to model other potent ligands, including 8-(3-chlorostyryl)caffeine, a new A2-selective antagonist, that could all be accommodated consistent with earlier biochemical and pharmacological findings [7].

Associations of Csc cpd with other chemical compounds


Gene context of Csc cpd


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  7. Molecular modeling of adenosine receptors. The ligand binding site on the rat adenosine A2A receptor. IJzerman, A.P., van der Wenden, E.M., van Galen, P.J., Jacobson, K.A. Eur. J. Pharmacol. (1994) [Pubmed]
  8. Partial agonism of the nonselective adenosine receptor agonist 8-butylaminoadenosine at the A1 receptor in vivo. Mathot, R.A., Wenden, E.M., Soudijn, W., Breimer, D.D., Ijzerman, A.P., Danhof, M. J. Pharmacol. Exp. Ther. (1996) [Pubmed]
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