Disease relevance of Calypso

• Athila4 of Arabidopsis and Calypso of soybean define a lineage of endogenous plant retroviruses [1].
• Target localization and real-time tracking using the Calypso 4D localization system in patients with localized prostate cancer [2].
• An octaploid (Fragaria x ananassa cv. Calypso) genotype of strawberry was transformed with an antisense chalcone synthase (CHS) gene construct using a ripening related CHS cDNA from Fragaria x ananassa cv. Elsanta under the control of the constitutive CaMV 35S promoter via Agrobacterium tumefaciens [3].
• The potential synergistic enhancement of the toxicity of thiacloprid to honeybees when co-applied with such fungicides was therefore studied under laboratory and semi-field conditions [4].

High impact information on Calypso

• Gag and Pol are encoded on a single open reading frame (ORF) of 1801 (Calypso) and 1911 (Athila4) amino acids [1].
• Consensus Calypso and Athila4 elements are 12-14 kb in length and have long terminal repeats of 1.3-1.8 kb [1].
• Imidacloprid, thiacloprid, and their imine analogs are not antinociceptive agents in mice by abdominal constriction and hot plate analgesic tests [5].
• We found that imidacloprid (IMI) (one of the most important insecticides) and thiacloprid (THIA) increased [(3)H]nicotine binding levels (up-regulation of the alpha 4 beta 2 AChRs) by five- to eightfold with EC50s of approximately 70,000 and 19,000 nM, respectively, compared with 760 nM for (-)-nicotine [6].
• Efficient levels of regeneration--those needed to carry out transformation experiments--with the cultivars Calypso, Pegasus, Bolero, Tango and Emily were achieved with leaf discs, petioles, roots and stipules [7].

Chemical compound and disease context of Calypso

• Azinphosmethyl had the highest levels of toxicity and shortest lethal time values, followed by the neonicotinoids thiacloprid, thiamethoxam, and imidacloprid, whereas indoxacarb had the highest LD50 and LT50 values for topical exposure [8].

Biological context of Calypso

• Thiacloprid, thiamethoxam, and imidacloprid showed oviposition deterrence, antifeedant, and repellency effects in the 7- and/or 14 d residual bioassays and protected fruit in the absence of significant lethal activity [8].

Associations of Calypso with other chemical compounds

• The ELISA exhibited satisfactory sensitivity (I (50) 0.6 ng/g; limit of detection 0.053 ng/g) and a high selectivity for acetamiprid versus other neonicotinoid analogs (thiacloprid amide) [9].
• We evaluated various doses of the systemic insecticides azadirachtin, emamectin benzoate, imidacloprid, and thiacloprid for control of A. glabripennis in naturally infested elms (Ulmus spp.), poplars (Populus spp.), and willows (Salix spp. ) in China between 2000 and 2002 [10].

Analytical, diagnostic and therapeutic context of Calypso

• PURPOSE: The Calypso 4D Localization System is being developed to provide accurate, precise, objective, and continuous target localization during radiotherapy [2].

References