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Chemical Compound Review

Technetium Tc 99m mertiatide     2-[2-[2-(2- sulfanylethanoylamino) ethanoyla...

Synonyms: Mertiatide, MAG3, CHEMBL1615778, AC1L1TWK, CTK8J9246, ...
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Disease relevance of Mertiatide

  • BACKGROUND: Renal scintigraphy with radiolabeled pentetic acid (diethylenetriamine pentaacetic acid [DTPA]) or, more recently, mertiatide (mercaptoacetyltriglycine [MAG3]), with or without captopril challenge, is widely recommended as a diagnostic test for renal artery stenosis [1].
  • METHODS: From a large data basis, we found retrospectively only 29 children (10 below and 19 above two years of age at first examination) having had at least two Tc-99m mertiatide (Tc-99m MAG3) renographic explorations for various urological diseases, with a decrease of split function of at least 5% between the two examinations [2].

High impact information on Mertiatide


Analytical, diagnostic and therapeutic context of Mertiatide


  1. The place of renal scintigraphy in the diagnosis of renal artery stenosis. Fifteen years of clinical experience. van Jaarsveld, B.C., Krijnen, P., Derkx, F.H., Oei, H.Y., Postma, C.T., Schalekamp, M.A. Arch. Intern. Med. (1997) [Pubmed]
  2. How to interpret a deterioration of split function? Piepsz, A., Ismaili, K., Hall, M., Collier, F., Tondeur, M., Ham, H. Eur. Urol. (2005) [Pubmed]
  3. The kidney: imaging with Tc-99m mercaptoacetyltriglycine, a technetium-labeled analog of iodohippurate. Russell, C.D., Thorstad, B.L., Stutzman, M.E., Yester, M.V., Fowler, D., Dubovsky, E.V. Radiology. (1989) [Pubmed]
  4. Technetium-99m radiopharmaceutical preparation problems: 12 years of experience. Ponto, J.A. Journal of nuclear medicine technology. (1998) [Pubmed]
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