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Gene Review

GLYS1  -  glycosuria 1, renal

Homo sapiens

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Disease relevance of GLYS1


Psychiatry related information on GLYS1


High impact information on GLYS1


Chemical compound and disease context of GLYS1


Biological context of GLYS1


Anatomical context of GLYS1


Associations of GLYS1 with chemical compounds

  • Epidemiologic study of abuse of analgesics containing phenacetin. Renal morbidity and mortality (1968-1979) [30].
  • 5. Renal ultrasound showed no correlation with VUR, and all DMSA scans but one were normal [31].
  • METHODS: Renal hemodynamics and tubular function were assessed by clearance techniques, before and after 100-microgram, 200-microgram, 400-microgram, or 800-microgram oral doses of misoprostol [32].
  • Letter; Renal failure and cephalothin [33].
  • CONCLUSIONS: (1) Renal functional reserve is absent in patients with early/asymptomatic HF and normal renal function and (2) both enalapril and losartan restore a normal vasodilatory response to AA in these patients without affecting basal systemic and renal hemodynamics [34].

Physical interactions of GLYS1

  • 4. Renal Mg2+ transport was similarly altered by hCT administration, without any evidence that prolonged CT inhibited renal Mg2+ transport [35].

Regulatory relationships of GLYS1


Other interactions of GLYS1


Analytical, diagnostic and therapeutic context of GLYS1


  1. Effect of the ownership of dialysis facilities on patients' survival and referral for transplantation. Garg, P.P., Frick, K.D., Diener-West, M., Powe, N.R. N. Engl. J. Med. (1999) [Pubmed]
  2. The effect of balloon angioplasty on hypertension in atherosclerotic renal-artery stenosis. Dutch Renal Artery Stenosis Intervention Cooperative Study Group. van Jaarsveld, B.C., Krijnen, P., Pieterman, H., Derkx, F.H., Deinum, J., Postma, C.T., Dees, A., Woittiez, A.J., Bartelink, A.K., Man in 't Veld, A.J., Schalekamp, M.A. N. Engl. J. Med. (2000) [Pubmed]
  3. Anaritide in acute tubular necrosis. Auriculin Anaritide Acute Renal Failure Study Group. Allgren, R.L., Marbury, T.C., Rahman, S.N., Weisberg, L.S., Fenves, A.Z., Lafayette, R.A., Sweet, R.M., Genter, F.C., Kurnik, B.R., Conger, J.D., Sayegh, M.H. N. Engl. J. Med. (1997) [Pubmed]
  4. Images in clinical medicine. Renal-vein thrombosis. Matthews, G.J., Hall, S. N. Engl. J. Med. (2000) [Pubmed]
  5. Light-chain nephropathy. Renal tubular dysfunction associated with light-chain proteinuria. Smithline, N., Kassirer, J.P., Cohen, J.J. N. Engl. J. Med. (1976) [Pubmed]
  6. Methylprednisolone and cyclophosphamide, alone or in combination, in patients with lupus nephritis. A randomized, controlled trial. Gourley, M.F., Austin, H.A., Scott, D., Yarboro, C.H., Vaughan, E.M., Muir, J., Boumpas, D.T., Klippel, J.H., Balow, J.E., Steinberg, A.D. Ann. Intern. Med. (1996) [Pubmed]
  7. Improvement in adequacy of delivered dialysis for adult in-center hemodialysis patients in the United States, 1993 to 1995. Helgerson, S.D., McClellan, W.M., Frederick, P.R., Beaver, S.K., Frankenfield, D.L., McMullan, M. Am. J. Kidney Dis. (1997) [Pubmed]
  8. Psychological correlates of survival on renal dialysis. Ziarnik, J.P., Freeman, C.W., Sherrard, D.J., Calsyn, D.A. J. Nerv. Ment. Dis. (1977) [Pubmed]
  9. Mucor pyelonephritis. Report of a case diagnosed by urine cytology, with diagnostic considerations in the workup of funguria. Florentine, B.D., Carriere, C., Abdul-Karim, F.W. Acta Cytol. (1997) [Pubmed]
  10. Pediatric nephrology in Rhode Island: experience of the Child Development Center Renal Clinic. Significant progress in diagnosis and treatment has been made. Brem, A.S., Abuelo, J.G. Rhode Island medical journal. (1980) [Pubmed]
  11. Images in clinical medicine. Renal-cell carcinoma extending into the vena cava and right side of the heart. Hunsaker, R.P., Stone, J.R. N. Engl. J. Med. (2001) [Pubmed]
  12. Effect of growth hormone treatment on the adult height of children with chronic renal failure. German Study Group for Growth Hormone Treatment in Chronic Renal Failure. Haffner, D., Schaefer, F., Nissel, R., Wühl, E., Tönshoff, B., Mehls, O. N. Engl. J. Med. (2000) [Pubmed]
  13. The economic implications of HLA matching in cadaveric renal transplantation. Schnitzler, M.A., Hollenbeak, C.S., Cohen, D.S., Woodward, R.S., Lowell, J.A., Singer, G.G., Tesi, R.J., Howard, T.K., Mohanakumar, T., Brennan, D.C. N. Engl. J. Med. (1999) [Pubmed]
  14. Poor long-term survival after acute myocardial infarction among patients on long-term dialysis. Herzog, C.A., Ma, J.Z., Collins, A.J. N. Engl. J. Med. (1998) [Pubmed]
  15. High survival rates of kidney transplants from spousal and living unrelated donors. Terasaki, P.I., Cecka, J.M., Gjertson, D.W., Takemoto, S. N. Engl. J. Med. (1995) [Pubmed]
  16. Epidemic of pediatric deaths from acute renal failure caused by diethylene glycol poisoning. Acute Renal Failure Investigation Team. O'Brien, K.L., Selanikio, J.D., Hecdivert, C., Placide, M.F., Louis, M., Barr, D.B., Barr, J.R., Hospedales, C.J., Lewis, M.J., Schwartz, B., Philen, R.M., St Victor, S., Espindola, J., Needham, L.L., Denerville, K. JAMA (1998) [Pubmed]
  17. Effect of renal-artery stenting on progression of renovascular renal failure. Harden, P.N., MacLeod, M.J., Rodger, R.S., Baxter, G.M., Connell, J.M., Dominiczak, A.F., Junor, B.J., Briggs, J.D., Moss, J.G. Lancet (1997) [Pubmed]
  18. Circulating levels of endothelin in cirrhosis. Asbert, M., Ginès, A., Ginès, P., Jiménez, W., Clària, J., Saló, J., Arroyo, V., Rivera, F., Rodés, J. Gastroenterology (1993) [Pubmed]
  19. Renal underexcretion of uric acid is present in patients with apparent high urinary uric acid output. Perez-Ruiz, F., Calabozo, M., Erauskin, G.G., Ruibal, A., Herrero-Beites, A.M. Arthritis Rheum. (2002) [Pubmed]
  20. {alpha}v{beta}6 Integrin Regulates Renal Fibrosis and Inflammation in Alport Mouse. Hahm, K., Lukashev, M.E., Luo, Y., Yang, W.J., Dolinski, B.M., Weinreb, P.H., Simon, K.J., Chun Wang, L., Leone, D.R., Lobb, R.R., McCrann, D.J., Allaire, N.E., Horan, G.S., Fogo, A., Kalluri, R., Shield, C.F., Sheppard, D., Gardner, H.A., Violette, S.M. Am. J. Pathol. (2007) [Pubmed]
  21. Images in clinical medicine. Renal-cell carcinoma. Sykes, J.S., McCarter, T.G. N. Engl. J. Med. (1998) [Pubmed]
  22. Glomerular hyperfiltration in patients with well-compensated alcoholic cirrhosis. Wong, F., Massie, D., Colman, J., Dudley, F. Gastroenterology (1993) [Pubmed]
  23. Renal failure in patients with cirrhosis and sepsis unrelated to spontaneous bacterial peritonitis: value of MELD score. Terra, C., Guevara, M., Torre, A., Gilabert, R., Fernández, J., Martín-Llahí, M., Baccaro, M.E., Navasa, M., Bru, C., Arroyo, V., Rodés, J., Ginès, P. Gastroenterology (2005) [Pubmed]
  24. Renal sodium retention during upright posture in preascitic cirrhosis. Bernardi, M., Di Marco, C., Trevisani, F., Fornalè, L., Andreone, P., Cursaro, C., Baraldini, M., Ligabue, A., Tamè, M.R., Gasbarrini, G. Gastroenterology (1993) [Pubmed]
  25. Four-year follow-up of Palmaz-Schatz stent revascularization as treatment for atherosclerotic renal artery stenosis. Dorros, G., Jaff, M., Mathiak, L., Dorros, I.I., Lowe, A., Murphy, K., He, T. Circulation (1998) [Pubmed]
  26. Arterial baroreflex control of renal hemodynamics in humans. van Tilborg, K.A., Rabelink, T.J., van Rijn, H.J., Boomsma, F., Koomans, H.A. Circulation (1994) [Pubmed]
  27. Electron microscopy of nephropathia epidemica. Renal tubular basement membrane. Collan, Y., Lähdevirta, J., Jokinen, E.J. Am. J. Pathol. (1978) [Pubmed]
  28. The association among renal insufficiency, pharmacotherapy, and outcomes in 6,427 patients with heart failure and coronary artery disease. Ezekowitz, J., McAlister, F.A., Humphries, K.H., Norris, C.M., Tonelli, M., Ghali, W.A., Knudtson, M.L. J. Am. Coll. Cardiol. (2004) [Pubmed]
  29. Patient survival on PAN/AN69 membrane hemodialysis: a ten-year analysis. Chandran, P.K., Liggett, R., Kirkpatrick, B. J. Am. Soc. Nephrol. (1993) [Pubmed]
  30. Epidemiologic study of abuse of analgesics containing phenacetin. Renal morbidity and mortality (1968-1979). Dubach, U.C., Rosner, B., Pfister, E. N. Engl. J. Med. (1983) [Pubmed]
  31. Screening of newborn babies for familial ureteric reflux. Scott, J.E., Swallow, V., Coulthard, M.G., Lambert, H.J., Lee, R.E. Lancet (1997) [Pubmed]
  32. Dose-dependent effects of oral misoprostol on renal function in alcoholic cirrhosis. Wong, F., Massie, D., Hsu, P., Dudley, F. Gastroenterology (1994) [Pubmed]
  33. Letter; Renal failure and cephalothin. Barrientos, A., Bello, I., Gutierrez-Millet, V. Ann. Intern. Med. (1976) [Pubmed]
  34. Early impairment of renal hemodynamic reserve in patients with asymptomatic heart failure is restored by angiotensin II antagonism. Magri, P., Rao, M.A., Cangianiello, S., Bellizzi, V., Russo, R., Mele, A.F., Andreucci, M., Memoli, B., De Nicola, L., Volpe, M. Circulation (1998) [Pubmed]
  35. Chronic calcitonin administration and renal calcium transport in the rat. Carney, S.L., Thompson, L. Clin. Exp. Pharmacol. Physiol. (1998) [Pubmed]
  36. Use of sirolimus and low-dose calcineurin inhibitor in lung transplant recipients with renal impairment: results of a controlled pilot study. Shitrit, D., Rahamimov, R., Gidon, S., Bakal, I., Bargil-Shitrit, A., Milton, S., Kramer, M.R. Kidney Int. (2005) [Pubmed]
  37. Analysis of mutations in the urate transporter 1 (URAT1) gene of Japanese patients with hypouricemia in northern Japan and review of the literature. Komatsuda, A., Iwamoto, K., Wakui, H., Sawada, K., Yamaguchi, A. Renal failure. (2006) [Pubmed]
  38. Multiple Acquired Renal Carcinoma Tumor Capabilities Abolished upon Silencing of ADAM17. Franovic, A., Robert, I., Smith, K., Kurban, G., Pause, A., Gunaratnam, L., Lee, S. Cancer Res. (2006) [Pubmed]
  39. Erythrocytosis after renal transplantation represents an abnormality of insulin-like growth factor-I and its binding proteins. Brox, A.G., Mangel, J., Hanley, J.A., St Louis, G., Mongrain, S., Gagnon, R.F. Transplantation (1998) [Pubmed]
  40. CC-Chemokine RANTES Is Increased in Serum and Urine in the Early Post-Transplantation Period of Human Renal Allograft Recipients. Baer, P.C., Koziolek, M., Fierlbeck, W., Geiger, H. Kidney Blood Press. Res. (2005) [Pubmed]
  41. Simvastatin Down Regulates mRNA Expression of RANTES and CCR5 in Posttransplant Renal Recipients With Hyperlipidemia. Li, Q., Wang, D., Wang, Y., Xu, Q. Transplant. Proc. (2006) [Pubmed]
  42. Effect of specific and non-specific inhibition of COX-2 on renal oxygenation before and after water diuresis. Gilbert, S., Zuo, C., Epstein, F.H. Nephron. Physiology [electronic resource]. (2005) [Pubmed]
  43. Renal transplantation in children. A report of the North American Pediatric Renal Transplant Cooperative Study. McEnery, P.T., Stablein, D.M., Arbus, G., Tejani, A. N. Engl. J. Med. (1992) [Pubmed]
  44. Effect of the use or nonuse of long-term dialysis on the subsequent survival of renal transplants from living donors. Mange, K.C., Joffe, M.M., Feldman, H.I. N. Engl. J. Med. (2001) [Pubmed]
  45. Predictors of type of vascular access in hemodialysis patients. Hirth, R.A., Turenne, M.N., Woods, J.D., Young, E.W., Port, F.K., Pauly, M.V., Held, P.J. JAMA (1996) [Pubmed]
  46. The TPA controversy and the drug approval process. The view of the Cardiovascular and Renal Drugs Advisory Committee. Kowey, P.R., Fisher, L., Giardina, E.G., Leier, C.V., Lowenthal, D.T., Messerli, F.H., Pratt, C.M. JAMA (1988) [Pubmed]
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