The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

Etarotene     6-[(E)-1-(4- ethylsulfonylphenyl)prop-1- en...

Synonyms: Etaroteno, Etarotenum, CHEMBL549872, SureCN636235, CCRIS 5451, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Etarotene


High impact information on Etarotene


Biological context of Etarotene

  • All tested compounds but one (Ro 15-1570) revealed a dose-dependent inhibition of RNase P activity, indicating that they may have a direct effect on tRNA biogenesis [3].

Associations of Etarotene with other chemical compounds


  1. Comparative teratogenicity of three retinoids: the arotinoids Ro 13-7410, Ro 13-6298 and Ro 15-1570. Kistler, A., Galli, B., Howard, W.B. Arch. Toxicol. (1990) [Pubmed]
  2. Regulation of the induction of ornithine decarboxylase in keratinocytes by retinoids. Zheng, Z.S., Xue, G.Z., Prystowsky, J.H. Biochem. J. (1995) [Pubmed]
  3. Retinoids inhibit human epidermal keratinocyte RNase P activity. Papadimou, E., Pavlidou, D., Séraphin, B., Tsambaos, D., Drainas, D. Biol. Chem. (2003) [Pubmed]
  4. Effects of retinoids and hydrocortisone on keratinocyte differentiation, epidermal growth factor binding and lipid metabolism. Ponec, M., Boonstra, J. Dermatologica (1987) [Pubmed]
WikiGenes - Universities