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Chemical Compound Review

CHEMBL22369     ethyl4-[(E)-2-(5,5,8,8- tetramethyl-6,7...

Synonyms: CCRIS 5450, SureCN2890175, AC1O5MYH, LS-38312, Ro-136298, ...
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Disease relevance of Arotinoid ethyl ester


High impact information on Arotinoid ethyl ester


Biological context of Arotinoid ethyl ester


  1. Effects of an inhibitor of cathepsin L on bone resorption in thyroparathyroidectomized and ovariectomized rats. Millest, A.J., Breen, S.A., Loveday, B.E., Clarkson, P.N., Simpson, C.A., Waterton, J.C., Johnstone, D. Bone (1997) [Pubmed]
  2. Arotinoids. A new class of retinoids with activities in oncology and dermatology. Bollag, W. Cancer Chemother. Pharmacol. (1981) [Pubmed]
  3. Treatment of cutaneous T-cell lymphoma with the arotinoid Ro 13-6298. Tousignant, J., Raymond, G.P., Light, M.J. J. Am. Acad. Dermatol. (1987) [Pubmed]
  4. Retinoic acid inhibition of IL-1-induced IL-6 production by human lung fibroblasts. Zitnik, R.J., Kotloff, R.M., Latifpour, J., Zheng, T., Whiting, N.L., Schwalb, J., Elias, J.A. J. Immunol. (1994) [Pubmed]
  5. Retinoid-dependent transcriptional suppression of cytokeratin gene expression in human epidermal squamous cell carcinoma cells. Agarwal, C., Rorke, E.A., Boyce, M., Howard, J., Crish, J., Hufeisen, S., Eckert, R.L. Differentiation (1993) [Pubmed]
  6. Arotinoid ethyl ester (Ro 13-6298): a long term pilot study in various dermatoses. Mérot, Y., Camenzind, M., Geiger, J.M., Saurat, J.H. Acta Derm. Venereol. (1987) [Pubmed]
  7. Effect of a new retinoid, arotinoid (Ro 13-6298), on in vitro keratinocyte proliferation and differentiation. Stadler, R., Marcelo, C.L., Voorhees, J.J., Orfanos, C.E. Acta Derm. Venereol. (1984) [Pubmed]
  8. Therapeutic effect of arotinoid Ro 13-6298 in psoriasis. Ott, F., Geiger, J.M. Arch. Dermatol. Res. (1983) [Pubmed]
  9. Evaluation of the sensitive step of inhibition of chondrogenesis by retinoids in limb mesenchymal cells in vitro. Zimmermann, B., Tsambaos, D. Cell Differ. (1985) [Pubmed]
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