Chemical Compound Review:
Orotaldehyde 2,6-dioxo-3H-pyrimidine-4- carbaldehyde
Synonyms:
OROTALALDEHYDE, CCRIS 8816, NSC-104159, AC1Q6BKA, AC1Q6PSS, ...
- Identification of repair enzymes for 5-formyluracil in DNA. Nth, Nei, and MutM proteins of Escherichia coli. Zhang, Q.M., Miyabe, I., Matsumoto, Y., Kino, K., Sugiyama, H., Yonei, S. J. Biol. Chem. (2000)
- 5-Formyluracil and its nucleoside derivatives confer toxicity and mutagenicity to mammalian cells by interfering with normal RNA and DNA metabolism. Klungland, A., Paulsen, R., Rolseth, V., Yamada, Y., Ueno, Y., Wiik, P., Matsuda, A., Seeberg, E., Bjelland, S. Toxicol. Lett. (2001)
- Enzymatic repair of 5-formyluracil. II. Mismatch formation between 5-formyluracil and guanine during dna replication and its recognition by two proteins involved in base excision repair (AlkA) and mismatch repair (MutS). Terato, H., Masaoka, A., Kobayashi, M., Fukushima, S., Ohyama, Y., Yoshida, M., Ide, H. J. Biol. Chem. (1999)
- Stable, specific, and reversible base pairing via Schiff base. Dohno, C., Okamoto, A., Saito, I. J. Am. Chem. Soc. (2005)
- Replication of DNA templates containing 5-formyluracil, a major oxidative lesion of thymine in DNA. Zhang, Q.M., Sugiyama, H., Miyabe, I., Matsuda, S., Saito, I., Yonei, S. Nucleic Acids Res. (1997)
- Mammalian 5-formyluracil-DNA glycosylase. 2. Role of SMUG1 uracil-DNA glycosylase in repair of 5-formyluracil and other oxidized and deaminated base lesions. Masaoka, A., Matsubara, M., Hasegawa, R., Tanaka, T., Kurisu, S., Terato, H., Ohyama, Y., Karino, N., Matsuda, A., Ide, H. Biochemistry (2003)
- Oxidation of thymine to 5-formyluracil in DNA: mechanisms of formation, structural implications, and base excision by human cell free extracts. Bjelland, S., Eide, L., Time, R.W., Stote, R., Eftedal, I., Volden, G., Seeberg, E. Biochemistry (1995)
- Mutagenic effects of 5-formyluracil on a plasmid vector during replication in Escherichia coli. Miyabe, I., Zhang, Q.M., Sugiyama, H., Kino, K., Yonei, S. Int. J. Radiat. Biol. (2001)
- Mutagenicity of 5-formyluracil in mammalian cells. Kamiya, H., Murata-Kamiya, N., Karino, N., Ueno, Y., Matsuda, A., Kasai, H. Nucleic Acids Symp. Ser. (2000)
- Cu(II) complexes with heterocyclic substituted thiosemicarbazones: the case of 5-formyluracil. Synthesis, characterization, x-ray structures, DNA interaction studies, and biological activity. Baldini, M., Belicchi-Ferrari, M., Bisceglie, F., Pelosi, G., Pinelli, S., Tarasconi, P. Inorganic chemistry. (2003)
- Replication in vitro and cleavage by restriction endonuclease of 5-formyluracil- and 5-hydroxymethyluracil-containing oligonucleotides. Zhang, Q.M., Sugiyama, H., Miyabe, I., Matsuda, S., Kino, K., Saito, I., Yonei, S. Int. J. Radiat. Biol. (1999)
- Synthesis, characterisation, X-ray structure and biological activity of three new 5-formyluracil thiosemicarbazone complexes. Ferrari, M.B., Bisceglie, F., Pelosi, G., Tarasconi, P., Albertin, R., Bonati, A., Lunghi, P., Pinelli, S. J. Inorg. Biochem. (2001)
- Identification of 5-formyluracil DNA glycosylase activity of human hNTH1 protein. Miyabe, I., Zhang, Q.M., Kino, K., Sugiyama, H., Takao, M., Yasui, A., Yonei, S. Nucleic Acids Res. (2002)
