Disease relevance of Lirohex

• To evaluate the pathogenesis of thrombosis formation in synthetic venous grafts, the inferior vena cava of rabbits were replaced by woven Tetron (polyethylene terephtalate) grafts [1].

High impact information on Lirohex

• We investigated the early response of peripheral blood gamma delta T cells to the nonpeptide Ag isopentenyl pyrophosphate and to its synthetic analogue ethyl pyrophosphate [2].
• Introduction of the enzyme poison tetraethyl pyrophosphate or the protein denaturant sodium fluoride into rat plasma had no significant effect on the half-life [3].
• Tetraethyl pyrophosphate at 100 micrograms/ml inhibited human plasma and red blood cell esterases permitting plasma protein binding and red blood cell partitioning studies [4].
• The spontaneous hydrolysis of the sampled biological fluids was inhibited by tetraethyl pyrophosphate so that the heroin concentration at the times of sampling could be analyzed for the first time [5].
• After treatment with organophosphorus cholinesterase inhibitors, such as di-isopropyl fluorophosphate and tetraethyl pyrophosphate, the uterus failed to respond to the acetate esters, even when high concentrations of choline were present [6].

Anatomical context of Lirohex

• To study blood compatibility of venous prosthesis made of textile or non-textile material, the inferior vena cava of 37 rabbits was partly replaced by 3 mm internal diameter synthetic tube graft made of textile material (T: woven tetron) or non-textile material (P: polytetrafluoroethylene) [7].

Associations of Lirohex with other chemical compounds

• Treatment of the erythrocytes with 1 X 10(-4) M tetraethylpyrophosphate prevented the inhibition of [3H]choline transport by acetylcholine mustard aziridinium ion [8].
• Eserine, tetraethyl pyrophosphate (TEPP) and diisopropyl fluorophosphate (DFP) also produced significant inhibition of VACV hydrolysis [9].

References