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Chemical Compound Review

PANTOLACTONE     3-hydroxy-4,4-dimethyl- oxolan-2-one

Synonyms: D-Pantolactone, SureCN152955, NSC-5926, NSC-8113, NSC-8114, ...
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Disease relevance of Pantoic lactone


High impact information on Pantoic lactone


Anatomical context of Pantoic lactone

  • Growth of Microccoccus lysodeikticus in the presence of pantoyl lactone brings about both qualitative and quantitative changes in cell membrane lipids [2].

Analytical, diagnostic and therapeutic context of Pantoic lactone


  1. Pantothenases from pseudomonads produce either pantoyl lactone or pantoic acid. Airas, R.K. Biochem. J. (1988) [Pubmed]
  2. Modification of cell membrane lipids in Micrococcus lysodeikticus induced by pantoyl lactone. Johnson, J.H., Grula, E.A., Staerkel, R., Fung, B.M., Mangum, B.L. J. Membr. Biol. (1980) [Pubmed]
  3. Effects of pantolactone and butyrolactone on the pleiotropic phenotypes of lon mutants and on thermal induction of the SOS phenomena in a tif mutant of Escherichia coli K12. Nakayama, H., Nakayama, K., Nakayama, R., Kato, Y. Arch. Microbiol. (1982) [Pubmed]
  4. Chemicals which promote survival of ultraviolet-irradiated lon and ruv mutants of Escherichia coli K12. Kato, Y., Shiraki, S., Hamada, Y., Iyehara-Ogawa, H., Nakayama, H. Can. J. Microbiol. (1980) [Pubmed]
  5. A screening system for enantioselective enzymes based on differential cell growth. Reetz, M.T., Rüggeberg, C.J. Chem. Commun. (Camb.) (2002) [Pubmed]
  6. The synthesis of deoxyfusapyrone. 1. An approach to the pyrone moiety. Organ, M.G., Wang, J. J. Org. Chem. (2002) [Pubmed]
  7. Analysis of stereochemistry of enzymically formed pantoyl lactone or pantoic acid by gas chromatography and circular dichroism. Wilken, D.R., Dyar, R.E. Anal. Biochem. (1981) [Pubmed]
  8. Cell membrane phospholipids and their constitutent fatty acids in dividing and nondividing cells of Micrococcus lysodeikticus. Johnson, J.H., Grula, E.A. Can. J. Microbiol. (1980) [Pubmed]
  9. Separation and determination of the enantiomers of pantolactone by gas-liquid chromatography. Takasu, A., Ohya, K. J. Chromatogr. (1987) [Pubmed]
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