Gene Review:
Tpr - translocated promoter region, nuclear...
Mus musculus
Synonyms:
2610029M07Rik, C77892, NPC-associated intranuclear protein, Nucleoprotein TPR, Translocated promoter region and nuclear basket protein
- K252a inhibits the oncogenic properties of Met, the HGF receptor. Morotti, A., Mila, S., Accornero, P., Tagliabue, E., Ponzetto, C. Oncogene (2002)
- Polyglutamine expansion of huntingtin impairs its nuclear export. Cornett, J., Cao, F., Wang, C.E., Ross, C.A., Bates, G.P., Li, S.H., Li, X.J. Nat. Genet. (2005)
- Identification of protein p270/Tpr as a constitutive component of the nuclear pore complex-attached intranuclear filaments. Cordes, V.C., Reidenbach, S., Rackwitz, H.R., Franke, W.W. J. Cell Biol. (1997)
- Enhanced transformation by a plasma membrane-associated met oncoprotein: activation of a phosphoinositide 3'-kinase-dependent autocrine loop involving hyaluronic acid and CD44. Kamikura, D.M., Khoury, H., Maroun, C., Naujokas, M.A., Park, M. Mol. Cell. Biol. (2000)
- Dimerization mediated through a leucine zipper activates the oncogenic potential of the met receptor tyrosine kinase. Rodrigues, G.A., Park, M. Mol. Cell. Biol. (1993)
- The mouse interferon-inducible gene Ifi204 product interacts with the Tpr protein, a component of the nuclear pore complex. De Andrea, M., Zannetti, C., Noris, E., Gariglio, M., Azzimonti, B., Landolfo, S. J. Interferon Cytokine Res. (2002)
- Signaling requirements for oncogenic forms of the Met tyrosine kinase receptor. Jeffers, M., Koochekpour, S., Fiscella, M., Sathyanarayana, B.K., Vande Woude, G.F. Oncogene (1998)
- Activating mutations in the Met receptor overcome the requirement for autophosphorylation of tyrosines crucial for wild type signaling. Jeffers, M.F. Oncogene (1999)
- Regulation of the urokinase-type plasminogen activator gene by the oncogene Tpr-Met involves GRB2. Besser, D., Bardelli, A., Didichenko, S., Thelen, M., Comoglio, P.M., Ponzetto, C., Nagamine, Y. Oncogene (1997)
- SU5416 is a potent inhibitor of hepatocyte growth factor receptor (c-Met) and blocks HGF-induced invasiveness of human HepG2 hepatoma cells. Wang, S.Y., Chen, B., Zhan, Y.Q., Xu, W.X., Li, C.Y., Yang, R.F., Zheng, H., Yue, P.B., Larsen, S.H., Sun, H.B., Yang, X. J. Hepatol. (2004)
- The evolutionarily conserved single-copy gene for murine Tpr encodes one prevalent isoform in somatic cells and lacks paralogs in higher eukaryotes. Kuznetsov, N.V., Sandblad, L., Hase, M.E., Hunziker, A., Hergt, M., Cordes, V.C. Chromosoma (2002)
- Product of the oncogene-activating gene Tpr is a phosphorylated protein of the nuclear pore complex. Bangs, P.L., Sparks, C.A., Odgren, P.R., Fey, E.G. J. Cell. Biochem. (1996)