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Gene Review

SF3B2  -  splicing factor 3b, subunit 2, 145kDa

Homo sapiens

Synonyms: Cus1, Pre-mRNA-splicing factor SF3b 145 kDa subunit, SAP 145, SAP145, SF3B145, ...
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Disease relevance of SF3B2


High impact information on SF3B2


Biological context of SF3B2


Anatomical context of SF3B2


Enzymatic interactions of SF3B2

  • Here we describe the identification of DYRK1A as a protein kinase that phosphorylates SF3b1 in vitro and in cultivated cells [4].

Other interactions of SF3B2

  • In addition to the RNA-binding activity of SAP 49, we show that this protein interacts directly and highly specifically with another U2 snRNP-associated spliceosomal protein, SAP 145 [3].


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