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Gene Review:

cat - chloramphenicol acetyltransferase

Agrobacterium fabrum str. C58

Herrera-Estrella, L. et al., Zaidenzaig, Y. et al., Kim, S.R. et al., Rogers, E.J. et al.

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Disease relevance of cat

A chimaeric gene, consisting of the 5'-flanking region of a member of the Pisum sativum gene family encoding ribulose 1,5-bisphosphate carboxylase linked to the coding region of a bacterial chloramphenicol acetyltransferase gene, has been introduced into the genome of the plant Nicotiana tabacum using a Ti plasmid of Agrobacterium tumefaciens [1].

High impact information on cat

Transgenic tobacco plants carrying a fusion between the nopaline synthase (nos) promoter and chloramphenicol acetyltransferase (CAT) reporter gene (cat) were studied for their inducibility by salicylic acid (SA) or methyl jasmonate (MJ) treatments [2].
The chloramphenicol acetyltransferase activity in all of the strains is chloramphenicol inducible [3].
4. Amino acid sequence analysis of the N-termini of selected variants suggests that the qualitative differences among chloramphenicol acetyltransferase variants is a reflection of structural heterogeneity which is most marked in comparisons between variants from Gram-positive and Gram-negative species [4].

References

Light-inducible and chloroplast-associated expression of a chimaeric gene introduced into Nicotiana tabacum using a Ti plasmid vector. Herrera-Estrella, L., Van den Broeck, G., Maenhaut, R., Van Montagu, M., Schell, J., Timko, M., Cashmore, A. Nature (1984) [Pubmed]
Identification of methyl jasmonate and salicylic acid response elements from the nopaline synthase (nos) promoter. Kim, S.R., Kim, Y., An, G. Plant Physiol. (1993) [Pubmed]
The chloramphenicol-inducible catB gene in Agrobacterium tumefaciens is regulated by translation attenuation. Rogers, E.J., Rahman, M.S., Hill, R.T., Lovett, P.S. J. Bacteriol. (2002) [Pubmed]
Characterization and comparison of chloramphenicol acetyltransferase variants. Zaidenzaig, Y., Fitton, J.E., Packman, L.C., Shaw, W.V. Eur. J. Biochem. (1979) [Pubmed]

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