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Gene Review

ARL11  -  ADP-ribosylation factor-like 11

Homo sapiens

Synonyms: ADP-ribosylation factor-like protein 11, ADP-ribosylation factor-like tumor suppressor protein 1, ARLTS1, FLJ33930
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Disease relevance of ARL11


High impact information on ARL11


Associations of ARL11 with chemical compounds

  • After its restoration by adenoviral transduction, ARLTS1-negative A549 and H1299 cells underwent apoptosis and inhibition of cell growth [8].

Biological context of ARL11


Anatomical context of ARL11


  1. Familial cancer associated with a polymorphism in ARLTS1. Calin, G.A., Trapasso, F., Shimizu, M., Dumitru, C.D., Yendamuri, S., Godwin, A.K., Ferracin, M., Bernardi, G., Chatterjee, D., Baldassarre, G., Rattan, S., Alder, H., Mabuchi, H., Shiraishi, T., Hansen, L.L., Overgaard, J., Herlea, V., Mauro, F.R., Dighiero, G., Movsas, B., Rassenti, L., Kipps, T., Baffa, R., Fusco, A., Mori, M., Russo, G., Liu, C.G., Neuberg, D., Bullrich, F., Negrini, M., Croce, C.M. N. Engl. J. Med. (2005) [Pubmed]
  2. Association of the ARLTS1 Cys148Arg variant with familial breast cancer risk. Frank, B., Hemminki, K., Meindl, A., Wappenschmidt, B., Klaes, R., Schmutzler, R.K., Untch, M., Bugert, P., Bartram, C.R., Burwinkel, B. Int. J. Cancer (2006) [Pubmed]
  3. ARLTS1 variants and melanoma risk. Frank, B., Meyer, P., Boettger, M.B., Hemminki, K., Stapelmann, H., Gast, A., Schmitt, C., Kumar, R., Sergi, C., Burwinkel, B. Int. J. Cancer (2006) [Pubmed]
  4. Cancer Familial Aggregation (CFA) and G446A polymorphism in ARLTS1 gene. Masojć, B., Mierzejewski, M., Cybulski, C., van de Wetering, T., Debniak, T., Górski, B., Jaworowska, E., Tarnowska, C., Lenner, M., Scott, R.J., Lubiński, J. Breast Cancer Res. Treat. (2006) [Pubmed]
  5. ARLTS1 variants and risk of colorectal cancer. Frank, B., Hemminki, K., Brenner, H., Hoffmeister, M., Chang-Claude, J., Burwinkel, B. Cancer Lett. (2006) [Pubmed]
  6. Association of the ARLTS1 Cys148Arg variant with sporadic and familial colorectal cancer. Castellví-Bel, S., Castells, A., de Cid, R., Muñoz, J., Balaguer, F., Gonzalo, V., Ruiz-Ponte, C., Andreu, M., Llor, X., Jover, R., Bessa, X., Xicola, R.M., Pons, E., Alenda, C., Payá, A., Carracedo, A., Piqué, J.M. Carcinogenesis (2007) [Pubmed]
  7. Relationship between ARLTS1 polymorphisms and risk of chronic lymphocytic leukemia. Sellick, G.S., Catovsky, D., Houlston, R.S. Leuk. Res. (2006) [Pubmed]
  8. Tumor suppressor functions of ARLTS1 in lung cancers. Yendamuri, S., Trapasso, F., Ferracin, M., Cesari, R., Sevignani, C., Shimizu, M., Rattan, S., Kuroki, T., Dumon, K.R., Bullrich, F., Liu, C.G., Negrini, M., Williams, N.N., Kaiser, L.R., Croce, C.M., Calin, G.A. Cancer Res. (2007) [Pubmed]
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