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Gene Review:

omp31-1 - hypothetical protein

Brucella suis 1330

Delpino, M.V. et al., Vizcaíno, N. et al., Jubier-Maurin, V. et al.

Vizcaíno, Caro-Hernández, Cloeckaert, Fernández-Lago,

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Disease relevance of omp31-1

Brucella outer membrane protein Omp31 is a haemin-binding protein [1].
IPTG-induced recombinant Escherichia coli cells expressing Omp31 on their membrane bound significantly more haemin than uninduced cells or controls carrying a similar plasmid without the omp31 gene, showing that Omp31 also binds haemin in a bacterial membrane environment [1].

High impact information on omp31-1

For this purpose, omp25 and omp31 null mutants of B. suis (Deltaomp25 B. suis and Deltaomp31 B. suis, respectively) were constructed and analyzed for the ability to activate human macrophages to secrete TNF-alpha [2].
DNA polymorphism in the omp25/omp31 family of Brucella spp.: identification of a 1.7-kb inversion in Brucella cetaceae and of a 15.1-kb genomic island, absent from Brucella ovis, related to the synthesis of smooth lipopolysaccharide [3].

References

Brucella outer membrane protein Omp31 is a haemin-binding protein. Delpino, M.V., Cassataro, J., Fossati, C.A., Goldbaum, F.A., Baldi, P.C. Microbes Infect. (2006) [Pubmed]
Major outer membrane protein Omp25 of Brucella suis is involved in inhibition of tumor necrosis factor alpha production during infection of human macrophages. Jubier-Maurin, V., Boigegrain, R.A., Cloeckaert, A., Gross, A., Alvarez-Martinez, M.T., Terraza, A., Liautard, J., Köhler, S., Rouot, B., Dornand, J., Liautard, J.P. Infect. Immun. (2001) [Pubmed]
DNA polymorphism in the omp25/omp31 family of Brucella spp.: identification of a 1.7-kb inversion in Brucella cetaceae and of a 15.1-kb genomic island, absent from Brucella ovis, related to the synthesis of smooth lipopolysaccharide. Vizcaíno, N., Caro-Hernández, P., Cloeckaert, A., Fernández-Lago, L. Microbes Infect. (2004) [Pubmed]

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