Disease relevance of Cyb561

• Mouse cytochrome b561: cDNA cloning and expression in rat brain, mouse embryos, and human glioma cell lines [1].

High impact information on Cyb561

• Human Erythrocyte Membranes Contain a Cytochrome b561 That May Be Involved in Extracellular Ascorbate Recycling [2].
• Genetic mapping of the gene encoding cytochrome b561 to mouse chromosome 11 [3].
• A cDNA encoding cytochrome b561 has been isolated from a mouse brain cDNA library, which predicts a protein of 250 amino acids with a deduced Mr of 27,770 [1].
• Cytochrome b561 expression was detectable in the 11-day-old mouse embryo, and the level of its mRNA increased tenfold by 15 and 17 days of gestation [1].
• This result indicates that a five transmembrane domain model best represents the conformation of cytochrome b561 in membranes [4].

Anatomical context of Cyb561

• Xenopus cytochrome b561: molecular confirmation of a general five transmembrane structure and developmental regulation at the gastrula stage [4].

References