Gene Review:
Cyp8b1 - cytochrome P450, family 8, subfamily b,...
Mus musculus
Synonyms:
7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase, 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase, CYPVIIIB1, Cyp12, Cytochrome P450 8B1, ...
- Impaired negative feedback suppression of bile acid synthesis in mice lacking betaKlotho. Ito, S., Fujimori, T., Furuya, A., Satoh, J., Nabeshima, Y., Nabeshima, Y. J. Clin. Invest. (2005)
- Cholic acid mediates negative feedback regulation of bile acid synthesis in mice. Li-Hawkins, J., Gåfvels, M., Olin, M., Lund, E.G., Andersson, U., Schuster, G., Björkhem, I., Russell, D.W., Eggertsen, G. J. Clin. Invest. (2002)
- Two loci on chromosome 9 control bile acid composition: evidence that a strong candidate gene, Cyp8b1, is not the culprit. Sehayek, E., Hagey, L.R., Fung, Y.Y., Duncan, E.M., Yu, H.J., Eggertsen, G., Björkhem, I., Hofmann, A.F., Breslow, J.L. J. Lipid Res. (2006)
- Regulation of bile acid biosynthesis by hepatocyte nuclear factor 4alpha. Inoue, Y., Yu, A.M., Yim, S.H., Ma, X., Krausz, K.W., Inoue, J., Xiang, C.C., Brownstein, M.J., Eggertsen, G., Björkhem, I., Gonzalez, F.J. J. Lipid Res. (2006)
- Critical role of cholic acid for development of hypercholesterolemia and gallstones in diabetic mice. Wang, J., Gåfvels, M., Rudling, M., Murphy, C., Björkhem, I., Einarsson, C., Eggertsen, G. Biochem. Biophys. Res. Commun. (2006)