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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

TMTC3  -  transmembrane and tetratricopeptide repeat...

Homo sapiens

Synonyms: FLJ90492, Protein SMILE, SMILE, Transmembrane and TPR repeat-containing protein 3
 
 
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Disease relevance of TMTC3

  • Survey of the patients with cleft lip and palate in China who were funded for surgery by the Smile Train Program from 2000 to 2002 [1].
 

Psychiatry related information on TMTC3

  • Stereopsis was measured with the MDRS test on two occasions, plus the Frisby, Randot, or Stereo Smile tests, as was age appropriate [2].
 

High impact information on TMTC3

  • Operation Smile: plastic surgery with few resources [3].
  • METHODS: Anesthesia providers and nurses participating in care of patients undergoing reconstructive plastic and orthopedic surgery by Operation Smile over an 18-month period were asked to complete a quality assurance data record for each case [4].
  • For detection of strabismus, the most accurate tests were the MTI Photoscreener (65%), the cover-uncover test (60%), the Stereo Smile II stereoacuity test (58%), the SureSight Vision Screener (54%), and the Retinomax Autorefractor (54% in year 1, 53% in year 2) [5].
  • This study assessed epidemiology and some genetic aspects of cleft lip and palate in a Chinese sample from the Smile Train Program and to compare with other methodologically sound surveys [1].
  • Sequential analysis found developmental changes from cycling between Gaze Elsewhere and Simple Attention to the Mother's Face in the early weeks to a complex sequence of transitions between Concentrated Attention, Smile, and Cooing Expression nested into sequences of positive communication during the 2nd and 3rd months [6].
 

Biological context of TMTC3

  • An evaluation of the Alabama Smile Keeper Dental Health Education Program was necessary to determine if educating teachers to teach preventive dentistry improved the oral hygiene and knowledge of dental health of elementary schoolchildren [7].
  • This year, the campaign's primary focus will not be mastication, function, freedom from disease or pain, but "Celebration of the Smile." A Smile is infectious, it's contagious, and one of the world's greatest bargains [8].
 

Analytical, diagnostic and therapeutic context of TMTC3

  • Under the sponsorship of Operation Smile International, clinical, genetic, and epidemiologic studies were carried out at six sites within the Philippines between 1989 and 1996 [9].
  • In response, the Smile Alabama! initiative was designed to improve oral health care services for Medicaid-eligible children by increasing the number of participating dentists by 15% and the number of children receiving dental care annually by 5% by January 31, 2004 [10].

References

  1. Survey of the patients with cleft lip and palate in China who were funded for surgery by the Smile Train Program from 2000 to 2002. Zhou, Q.J., Shi, B., Shi, Z.D., Zheng, Q., Wang, Y. Chin. Med. J. (2006) [Pubmed]
  2. The moving Dynamic Random Dot Stereosize test: development, age norms, and comparison with the Frisby, Randot, and Stereo Smile tests. Leat, S.J., Pierre, J.S., Hassan-Abadi, S., Faubert, J. Journal of pediatric ophthalmology and strabismus. (2001) [Pubmed]
  3. Operation Smile: plastic surgery with few resources. Bermudez, L.E. Lancet (2000) [Pubmed]
  4. Assessing pediatric anesthesia practices for volunteer medical services abroad. Fisher, Q.A., Nichols, D., Stewart, F.C., Finley, G.A., Magee, W.P., Nelson, K. Anesthesiology (2001) [Pubmed]
  5. Sensitivity of screening tests for detecting vision in preschoolers-targeted vision disorders when specificity is 94%. Ying, G.S., Kulp, M.T., Maguire, M., Ciner, E., Cyert, L., Schmidt, P. Optometry and vision science : official publication of the American Academy of Optometry. (2005) [Pubmed]
  6. Developmental changes in the relationship between the infant's attention and emotion during early face-to-face communication: the 2-month transition. Lavelli, M., Fogel, A. Developmental psychology. (2005) [Pubmed]
  7. An assessment of the Alabama Smile Keeper school dental health education program. Rose, C., Rogers, E.W., Kleinman, P.R., Shory, N.L., Meehan, J.T., Zumbro, P.E. Journal of the American Dental Association (1939) (1979) [Pubmed]
  8. "Celebration of the smile". Crawford, P.R. Journal (Canadian Dental Association) (1989) [Pubmed]
  9. Clinical and epidemiologic studies of cleft lip and palate in the Philippines. Murray, J.C., Daack-Hirsch, S., Buetow, K.H., Munger, R., Espina, L., Paglinawan, N., Villanueva, E., Rary, J., Magee, K., Magee, W. The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association. (1997) [Pubmed]
  10. Smile Alabama! Initiative: interim results from a program to increase children's access to dental care. Greene-McIntyre, M., Finch, M.H., Searcy, J. The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association. (2003) [Pubmed]
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