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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Oral Hygiene

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Disease relevance of Oral Hygiene

  • In the other two patients, lowering of the verapamil dose, in addition to optimal oral hygiene and dental plaque control, was necessary; in one patient verapamil had to be stopped completely to reverse the gingival enlargement [1].
  • Standard care for oral mucositis is based on effective oral hygiene, appropriate analgesia, infection management, and parenteral nutrition when needed; few other approaches have been shown to be effective [2].
  • The oral hygiene, plaque and gingival index scores were greater (p < 0.0001), oral clearance was longer (p < 0.01), and levels of sucrose and starch-derived saccharides higher (p < 0.01) in the cleft palate group [3].
  • Caries prevalence, oral hygiene index, submandibular gland hypertrophy, occlusion, dental hypoplasia, and staining of permanent teeth were evaluated in 63 patients with cystic fibrosis (CF) who were maintained on a regimen of broad-spectrum antibiotics and oral pancreatin, and the findings were compared with those of their near-aged siblings [4].
  • It was concluded that the use of Perimed could be a beneficial adjunctive treatment for the prevention and control of gingivitis when used with routine oral hygiene procedures [5].

Psychiatry related information on Oral Hygiene

  • In addition, the students were interviewed with regard to oral hygiene, topical fluoride application, and dietary habits [6].
  • Data on behaviors and attitudes were collected via a self-administered questionnaire having six domains: (i) family background; (ii) dental anxiety; (iii) dental utilization; (iv) oral hygiene; (v) use of fluoride toothpaste; and (vi) sugar consumption [7].
  • OBJECTIVE: To determine the influence of oral hygiene practices and additional fluoride on erosive tooth wear in eating disorders [8].
  • Organoleptic and gas chromatographic methods were employed to establish the threshold of odor objectionability of methylmercaptan and hydrogen sulfide and to assess the relative effectiveness of different oral hygiene measures to reduce the malodor to acceptable levels [9].
  • Boys reported more risk-taking behaviors than did girls; White youth had lower injury-prevention scores than Black youth; and younger children and children with behavior or emotional disorders in specialized classrooms reported fewer health promotion activities related to nutrition, exercise, and dental hygiene [10].

High impact information on Oral Hygiene


Chemical compound and disease context of Oral Hygiene


Biological context of Oral Hygiene


Anatomical context of Oral Hygiene

  • Control of occlusal caries in the first permanent molars by oral hygiene [26].
  • Besides oral hygiene, the test group rinsed 2x daily with 0.2% chlorhexidine and sprayed the tonsils with a 0.2% chlorhexidine for 2 months [27].
  • In order to gain further understanding of the role of chemokines in healthy oral mucosa, we analyzed mRNA expression of the alpha (CXC)-family chemokines IL-8 and GROgamma as well as of the beta (CC)-family chemokines MIP-1alpha, MIP-1beta and MCP-1 in twenty young and healthy subjects with good oral hygiene [28].
  • The purpose of the present study was to determine if there were differences in the quantity of accessible sialic acid on superficial epithelial cells collected from different areas of the mouth, and from healthy subjects with good oral hygiene, as compared to subjects with gingivitis [29].
  • The data obtained suggest that the oral hygiene status of an individual can influence the quantity of accessible sialic acid residues on oral epithelium; this would be expected to influence the attachment and colonization of bacteria which bind to sialic acid-containing receptors [29].

Associations of Oral Hygiene with chemical compounds

  • Oral hygiene also reduced the occurrence and magnitude of the early hydrogen rise after lactulose ingestion [13].
  • The recolonization of the pockets was retarded by oral hygiene and 0.2% chlorhexidine rinses during two weeks [30].
  • This study showed that smoking was the most important factor affecting the rate of peri-implant bone loss, and that oral hygiene also had an influence, especially in smokers, while other factors, e.g., those associated with occlusal loading, were of minor importance [31].
  • Two-hundred and fourteen subjects ranging in age from 22 to 63 years used either a mouthwash that contained 0.035% w/v alexidine.2HCL (2-ethylhexyl bisbiguanidine dihydrochloride) or a placebo twice daily on a doubleblind basis for six months in conjunction with routine oral hygiene procedures [32].
  • Triclosan is a broad-spectrum hydrophobic antibacterial agent used in dermatological preparations and oral hygiene products [33].

Gene context of Oral Hygiene

  • ROH reduced GI, BOP and PI, and PGE2 levels by 14 days, but had no effect on IL-1 beta or IL-10 levels relative to no oral hygiene [34].
  • Their levels increased significantly from baseline and remained high for at least one week after the reinstitution of oral hygiene measures (repeated measures MANOVA; alpha 2-M: p = 0.015; alpha 1-AT: p = 0.012; TF: p = 0.02) [35].
  • Experimental evidence has clearly demonstrated that IL-1 cytokine levels increase in experimental gingivitis (EG) models in response to plaque accumulation following the cessation of oral hygiene [36].
  • In contrast to the serum derived acute-phase proteins, the neutrophil derived LF rose significantly from baseline (repeated measures MANOVA; p = 0.001) but dropped rapidly after the reinstitution of oral hygiene measures [35].
  • 50 RA patients were matched for age, sex, smoking and oral hygiene with 101 healthy controls [37].

Analytical, diagnostic and therapeutic context of Oral Hygiene

  • Three caries preventative regimens: oral hygiene; oral hygiene and topical fluoride; and oral hygiene, typical fluoride, and sucrose restriction were evaluated in patients with cancer given xerostomia-producing radiotherapy [38].
  • The aim of this study was to determine effect of initial therapy including oral hygiene instruction and scaling and root planing (SRP) on sulcular/tongue sulfide level [39].
  • In conclusion, chlorhexidine has significant adjunctive effects on plaque inhibition in the presence of normal unsupervised oral hygiene, but toothbrushing did not prevent toothstaining [40].
  • Following oral hygiene instruction and root debridement at baseline, test teeth were irrigated subgingivally by a professional with a solution of 50 mg/ml of tetracycline, and control teeth with saline every 2nd week for 3 months [41].
  • We considered the following variables: gender, daily CsA dose, duration of immunosuppressive treatment, CsA plasma concentration, concomitant use of another immunosuppressive agent (azathioprine), use of other GO inducers (calcium channel blockers, anti-epileptic drugs), oral hygiene scores, and other drugs taken at the time of oral examination [42].


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  2. Mucosal damage: a major risk factor for severe complications after cytotoxic therapy. Peterson, D.E., Cariello, A. Semin. Oncol. (2004) [Pubmed]
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  13. Evaluation of the hydrogen breath test in man: definition and elimination of the early hydrogen peak. Mastropaolo, G., Rees, W.D. Gut (1987) [Pubmed]
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  17. Reduction of plaque formation and gingivitis by a dentifrice containing triclosan and copolymer. Kanchanakamol, U., Umpriwan, R., Jotikasthira, N., Srisilapanan, P., Tuongratanaphan, S., Sholitkul, W., Chat-Uthai, T. J. Periodontol. (1995) [Pubmed]
  18. Slow release metronidazole and a simplified mechanical oral hygiene regimen in the control of chronic periodontitis. Newman, H.N., Yeung, F.I., wan Yusof, W.Z., Addy, M. Journal of clinical periodontology. (1984) [Pubmed]
  19. The effect of a mouth rinse containing phenolic compounds on plaque formation and developing gingivitis. Sekino, S., Ramberg, P. Journal of clinical periodontology. (2005) [Pubmed]
  20. The effect of a dentifrice and mouth rinse combination containing amine fluoride/stannous fluoride on plaque and gingivitis: a 6-month field study. Paraskevas, S., Versteeg, P.A., Timmerman, M.F., Van der Velden, U., Van der Weijden, G.A. Journal of clinical periodontology. (2005) [Pubmed]
  21. Specific IgE-dependent sensitization, atopy, and bronchial hyperresponsiveness in apprentices starting exposure to protein-derived agents. Gautrin, D., Infante-Rivard, C., Dao, T.V., Magnan-Larose, M., Desjardins, D., Malo, J.L. Am. J. Respir. Crit. Care Med. (1997) [Pubmed]
  22. Exposure to low levels of fluoride and dental caries in deciduous molars of Tanzanian children. Frencken, J.E., König, K.G., Mulder, J., Truin, G.J. Caries Res. (1992) [Pubmed]
  23. Dentistry's commitment to Head Start: an evaluation of selected programs. Parker, W.A., Fultz, R.P. Journal of the American Dental Association (1939) (1986) [Pubmed]
  24. Sugar intake, taste changes and dental health in Crohn's disease. Schütz, T., Drude, C., Paulisch, E., Lange, K.P., Lochs, H. Digestive diseases (Basel, Switzerland) (2003) [Pubmed]
  25. Initial therapy for the periodontally diseased patient. Levine, D.F., Green, M.S. Journal of the California Dental Association. (1993) [Pubmed]
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  27. The effect of a one-stage full-mouth disinfection on different intra-oral niches. Clinical and microbiological observations. Bollen, C.M., Mongardini, C., Papaioannou, W., Van Steenberghe, D., Quirynen, M. Journal of clinical periodontology. (1998) [Pubmed]
  28. Chemokine gene expression in human oral mucosa. Zehnder, M., Greenspan, J.S., Greenspan, D., Bickel, M. Eur. J. Oral Sci. (1999) [Pubmed]
  29. Accessible sialic acid content of oral epithelial cells from healthy and gingivitis subjects. Davis, G., Gibbons, R.J. J. Periodont. Res. (1990) [Pubmed]
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  32. Effects of alexidine.2HCL mouthwash on plaque and gingivitis after six months. Spolsky, V.W., Forsythe, A.B. J. Dent. Res. (1977) [Pubmed]
  33. Membranotropic effects of the antibacterial agent Triclosan. Villalaín, J., Mateo, C.R., Aranda, F.J., Shapiro, S., Micol, V. Arch. Biochem. Biophys. (2001) [Pubmed]
  34. Clinical benefits of oral irrigation for periodontitis are related to reduction of pro-inflammatory cytokine levels and plaque. Cutler, C.W., Stanford, T.W., Abraham, C., Cederberg, R.A., Boardman, T.J., Ross, C. Journal of clinical periodontology. (2000) [Pubmed]
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  42. Cyclosporin-induced gingival overgrowth: a clinical-epidemiological evaluation of 121 Italian renal transplant recipients. Vescovi, P., Meleti, M., Manfredi, M., Merigo, E., Pedrazzi, G. J. Periodontol. (2005) [Pubmed]
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