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Gene Review

Limk2  -  LIM motif-containing protein kinase 2

Mus musculus

Synonyms: A930024P04Rik, C85310, LIM domain kinase 2, LIM kinase 2, LIMK-2, ...
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High impact information on Limk2


Biological context of Limk2


Analytical, diagnostic and therapeutic context of Limk2

  • Northern blot analysis showed Limk2a mRNA was ubiquitously present in various adult tissues, while Limbk2b was predominantly expressed in brain [3].


  1. Impaired spermatogenic ability of testicular germ cells in mice deficient in the LIM-kinase 2 gene. Takahashi, H., Koshimizu, U., Miyazaki, J., Nakamura, T. Dev. Biol. (2002) [Pubmed]
  2. Mouse LIM-kinase 2 gene: cDNA cloning, genomic organization, and tissue-specific expression of two alternatively initiated transcripts. Ikebe, C., Ohashi, K., Fujimori, T., Bernard, O., Noda, T., Robertson, E.J., Mizuno, K. Genomics (1997) [Pubmed]
  3. cDNA cloning, genomic organization, and chromosomal localization of the mouse LIM motif-containing kinase gene, Limk2. Koshimizu, U., Takahashi, H., Yoshida, M.C., Nakamura, T. Biochem. Biophys. Res. Commun. (1997) [Pubmed]
  4. A novel transcript encoding truncated LIM kinase 2 is specifically expressed in male germ cells undergoing meiosis. Takahashi, H., Koshimizu, U., Nakamura, T. Biochem. Biophys. Res. Commun. (1998) [Pubmed]
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