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Gene Review

tbg-1  -  Protein TBG-1

Caenorhabditis elegans

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  • In this article we characterize, from a structural point of view, all 16 members of the tubulin gene family of Caenorhabditis elegans (9 alpha-tubulins, 6 beta-tubulins, and 1 gamma-tubulin) [7].


  1. Katanin controls mitotic and meiotic spindle length. McNally, K., Audhya, A., Oegema, K., McNally, F.J. J. Cell Biol. (2006) [Pubmed]
  2. The kinetically dominant assembly pathway for centrosomal asters in Caenorhabditis elegans is gamma-tubulin dependent. Hannak, E., Oegema, K., Kirkham, M., Gönczy, P., Habermann, B., Hyman, A.A. J. Cell Biol. (2002) [Pubmed]
  3. Aurora-A kinase is required for centrosome maturation in Caenorhabditis elegans. Hannak, E., Kirkham, M., Hyman, A.A., Oegema, K. J. Cell Biol. (2001) [Pubmed]
  4. Spindle dynamics and the role of gamma-tubulin in early Caenorhabditis elegans embryos. Strome, S., Powers, J., Dunn, M., Reese, K., Malone, C.J., White, J., Seydoux, G., Saxton, W. Mol. Biol. Cell (2001) [Pubmed]
  5. Asymmetrization of first cleavage by transient disassembly of one spindle pole aster in the leech Helobdella robusta. Ren, X., Weisblat, D.A. Dev. Biol. (2006) [Pubmed]
  6. Centrosome maturation and mitotic spindle assembly in C. elegans require SPD-5, a protein with multiple coiled-coil domains. Hamill, D.R., Severson, A.F., Carter, J.C., Bowerman, B. Dev. Cell (2002) [Pubmed]
  7. Computational prediction of the three-dimensional structures for the Caenorhabditis elegans tubulin family. Gogonea, C.B., Gogonea, V., Ali, Y.M., Merz, K.M., Siddiqui, S.S. J. Mol. Graph. Model. (1999) [Pubmed]
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