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Ddr2  -  discoidin domain receptor family, member 2

Mus musculus

Synonyms: AW495251, CD167 antigen-like family member B, Discoidin domain receptor 2, Discoidin domain-containing receptor 2, Neurotrophic tyrosine kinase, receptor-related 3, ...
 
 
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Disease relevance of Ddr2

  • Activation of the discoidin domain receptor 2 induces expression of matrix metalloproteinase 13 associated with osteoarthritis in mice [1].
 

High impact information on Ddr2

 

Associations of Ddr2 with chemical compounds

 

Analytical, diagnostic and therapeutic context of Ddr2

References

  1. Activation of the discoidin domain receptor 2 induces expression of matrix metalloproteinase 13 associated with osteoarthritis in mice. Xu, L., Peng, H., Wu, D., Hu, K., Goldring, M.B., Olsen, B.R., Li, Y. J. Biol. Chem. (2005) [Pubmed]
  2. Discoidin domain receptor 2 regulates fibroblast proliferation and migration through the extracellular matrix in association with transcriptional activation of matrix metalloproteinase-2. Olaso, E., Labrador, J.P., Wang, L., Ikeda, K., Eng, F.J., Klein, R., Lovett, D.H., Lin, H.C., Friedman, S.L. J. Biol. Chem. (2002) [Pubmed]
  3. The collagen receptor DDR2 regulates proliferation and its elimination leads to dwarfism. Labrador, J.P., Azcoitia, V., Tuckermann, J., Lin, C., Olaso, E., Mañes, S., Brückner, K., Goergen, J.L., Lemke, G., Yancopoulos, G., Angel, P., Martínez, C., Klein, R. EMBO Rep. (2001) [Pubmed]
  4. Structure and expression of the Tyro 10 receptor tyrosine kinase. Lai, C., Lemke, G. Oncogene (1994) [Pubmed]
  5. Binding of discoidin domain receptor 2 to collagen I: an atomic force microscopy investigation. Agarwal, G., Kovac, L., Radziejewski, C., Samuelsson, S.J. Biochemistry (2002) [Pubmed]
 
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