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Gene Review

AQPEP  -  laeverin

Homo sapiens

Synonyms: APQ, FLJ90650, LVRN, TAQPEP
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High impact information on FLJ90650


Associations of FLJ90650 with chemical compounds

  • These results indicate that Laeverin/APQ is a novel bestatin-sensitive leucine aminopeptidase and suggest that the enzyme plays important roles in human placentation by regulating biological activity of key peptides at the embryo-maternal interface [3].


  1. Identification of genes modulated in rheumatoid arthritis using complementary DNA microarray analysis of lymphoblastoid B cell lines from disease-discordant monozygotic twins. Haas, C.S., Creighton, C.J., Pi, X., Maine, I., Koch, A.E., Haines, G.K., Ling, S., Chinnaiyan, A.M., Holoshitz, J. Arthritis Rheum. (2006) [Pubmed]
  2. Human extravillous trophoblasts express laeverin, a novel protein that belongs to membrane-bound gluzincin metallopeptidases. Fujiwara, H., Higuchi, T., Yamada, S., Hirano, T., Sato, Y., Nishioka, Y., Yoshioka, S., Tatsumi, K., Ueda, M., Maeda, M., Fujii, S. Biochem. Biophys. Res. Commun. (2004) [Pubmed]
  3. Laeverin/aminopeptidase Q, a novel bestatin-sensitive leucine aminopeptidase belonging to the M1 family of aminopeptidases. Maruyama, M., Hattori, A., Goto, Y., Ueda, M., Maeda, M., Fujiwara, H., Tsujimoto, M. J. Biol. Chem. (2007) [Pubmed]
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