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Gene Review

RABGAP1  -  RAB GTPase activating protein 1

Homo sapiens

Synonyms: GAP and centrosome-associated protein, GAPCENA, GAPCenA, HSPC094, Rab GTPase-activating protein 1, ...
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Disease relevance of RABGAP1


High impact information on RABGAP1


Biological context of RABGAP1


Other interactions of RABGAP1


Analytical, diagnostic and therapeutic context of RABGAP1


  1. PRC17, a novel oncogene encoding a Rab GTPase-activating protein, is amplified in prostate cancer. Pei, L., Peng, Y., Yang, Y., Ling, X.B., Van Eyndhoven, W.G., Nguyen, K.C., Rubin, M., Hoey, T., Powers, S., Li, J. Cancer Res. (2002) [Pubmed]
  2. A role for the Rab6A' GTPase in the inactivation of the Mad2-spindle checkpoint. Miserey-Lenkei, S., Couëdel-Courteille, A., Del Nery, E., Bardin, S., Piel, M., Racine, V., Sibarita, J.B., Perez, F., Bornens, M., Goud, B. EMBO J. (2006) [Pubmed]
  3. Characterization of GAPCenA, a GTPase activating protein for Rab6, part of which associates with the centrosome. Cuif, M.H., Possmayer, F., Zander, H., Bordes, N., Jollivet, F., Couedel-Courteille, A., Janoueix-Lerosey, I., Langsley, G., Bornens, M., Goud, B. EMBO J. (1999) [Pubmed]
  4. Alternative splicing of the human Rab6A gene generates two close but functionally different isoforms. Echard, A., Opdam, F.J., de Leeuw, H.J., Jollivet, F., Savelkoul, P., Hendriks, W., Voorberg, J., Goud, B., Fransen, J.A. Mol. Biol. Cell (2000) [Pubmed]
  5. Substrate specificity and effect on GLUT4 translocation of the Rab GTPase-activating protein Tbc1d1. Roach, W.G., Chavez, J.A., Mîinea, C.P., Lienhard, G.E. Biochem. J. (2007) [Pubmed]
  6. EVI5 is a novel centrosomal protein that binds to alpha- and gamma-tubulin. Faitar, S.L., Dabbeekeh, J.T., Ranalli, T.A., Cowell, J.K. Genomics (2005) [Pubmed]
  7. Identification of Rab GTPase-activating protein-like protein (RabGAPLP) as a novel Alix/AIP1-interacting protein. Ichioka, F., Horii, M., Katoh, K., Terasawa, Y., Shibata, H., Maki, M. Biosci. Biotechnol. Biochem. (2005) [Pubmed]
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