Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Gene Review:

orb6 - serine/threonine protein kinase Orb6

Schizosaccharomyces pombe 972h-

Verde, F. et al., Wiley, D.J. et al.

Verde, Wiley, Nurse,

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of orb6

Fission yeast orb6, a ser/thr protein kinase related to mammalian rho kinase and myotonic dystrophy kinase, is required for maintenance of cell polarity and coordinates cell morphogenesis with the cell cycle [1].

High impact information on orb6

Loss of Skb1p exacerbates the phenotype of orb6 mutants, suggesting that Skb1p and Orb6p functionally interact in S. pombe cells [2].

Chemical compound and disease context of orb6

The orb6 gene is required during interphase to maintain cell polarity and encodes a serine/threonine protein kinase, belonging to the myotonic dystrophy kinase/cot1/warts family [1].

References

Fission yeast orb6, a ser/thr protein kinase related to mammalian rho kinase and myotonic dystrophy kinase, is required for maintenance of cell polarity and coordinates cell morphogenesis with the cell cycle. Verde, F., Wiley, D.J., Nurse, P. Proc. Natl. Acad. Sci. U.S.A. (1998) [Pubmed]
Control of cell polarity in fission yeast by association of Orb6p kinase with the highly conserved protein methyltransferase Skb1p. Wiley, D.J., Marcus, S., D'urso, G., Verde, F. J. Biol. Chem. (2003) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

AgaP_AGAP005521	Anopheles gambiae str. PEST
AT1G30640	Arabidopsis thaliana
AGOS_AFR035W	Ashbya gossypii ATCC 10895
STK38L	Bos taurus
sax-1	Caenorhabditis elegans
STK38L	Canis lupus familiaris
stk38l	Danio rerio
trc	Drosophila melanogaster
STK38L	Gallus gallus
STK38L	Homo sapiens
KLLA0D07810g	Kluyveromyces lactis NRRL Y-1140
STK38L	Macaca mulatta
MGG_05376	Magnaporthe oryzae 70-15
Stk38l	Mus musculus
NCU07296	Neurospora crassa OR74A
Os05g0511400	Oryza sativa Japonica Group
STK38L	Pan troglodytes
Stk38l	Rattus norvegicus
CBK1	Saccharomyces cerevisiae S288c

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.