Gene Review:
RANP1 - RAN, member RAS oncogene family pseudogene 1
Homo sapiens
Synonyms:
Em:AB014080.2, Ras-like, TC4
- Elimination of the vertebrate Escherichia coli Ras-like protein homologue leads to cell cycle arrest at G1 phase and apoptosis. Gohda, J., Nomura, Y., Suzuki, H., Arai, H., Akiyama, T., Inoue, J. Oncogene (2003)
- GTP Binding Is Essential to the Protein Kinase Activity of LRRK2, a Causative Gene Product for Familial Parkinson's Disease. Ito, G., Okai, T., Fujino, G., Takeda, K., Ichijo, H., Katada, T., Iwatsubo, T. Biochemistry (2007)
- Trishomocubanes: Novel sigma ligands modulate cocaine-induced behavioural effects. Liu, X., Banister, S.D., Christie, M.J., Banati, R., Meikle, S., Coster, M.J., Kassiou, M. Eur. J. Pharmacol. (2007)
- GTPase-activating proteins for heterotrimeric G proteins: regulators of G protein signaling (RGS) and RGS-like proteins. Ross, E.M., Wilkie, T.M. Annu. Rev. Biochem. (2000)
- Regulation of the cytoskeleton and cell adhesion by the Rho family GTPases in mammalian cells. Kaibuchi, K., Kuroda, S., Amano, M. Annu. Rev. Biochem. (1999)
- A GDP dissociation inhibitor that serves as a GTPase inhibitor for the Ras-like protein CDC42Hs. Hart, M.J., Maru, Y., Leonard, D., Witte, O.N., Evans, T., Cerione, R.A. Science (1992)
- The Ras superfamilies: regulatory proteins and post-translational modifications. Evans, T., Hart, M.J., Cerione, R.A. Curr. Opin. Cell Biol. (1991)
- Evidence for a dual role for TC4 protein in regulating nuclear structure and cell cycle progression. Kornbluth, S., Dasso, M., Newport, J. J. Cell Biol. (1994)
- GTP-binding proteins in intracellular transport. Pfeffer, S.R. Trends Cell Biol. (1992)
- PRA1 inhibits the extraction of membrane-bound rab GTPase by GDI1. Hutt, D.M., Da-Silva, L.F., Chang, L.H., Prosser, D.C., Ngsee, J.K. J. Biol. Chem. (2000)
- Costimulation through CD28 suppresses T cell receptor-dependent activation of the Ras-like small GTPase Rap1 in human T lymphocytes. Reedquist, K.A., Bos, J.L. J. Biol. Chem. (1998)
- Phosphoinositides determine specificity of the guanine-nucleotide exchange activity of cytohesin-1 for ADP-ribosylation factors derived from a mammalian expression system. Knorr, T., Nagel, W., Kolanus, W. Eur. J. Biochem. (2000)
- Tissue-specific expression of Ran isoforms in the mouse. Coutavas, E.E., Hsieh, C.M., Ren, M., Drivas, G.T., Rush, M.G., D'Eustachio, P.D. Mamm. Genome (1994)
- Epac: a new cAMP target and new avenues in cAMP research. Bos, J.L. Nat. Rev. Mol. Cell Biol. (2003)
- Rap1GAP2 is a new GTPase-activating protein of Rap1 expressed in human platelets. Schultess, J., Danielewski, O., Smolenski, A.P. Blood (2005)
- Rap2B-dependent stimulation of phospholipase C-epsilon by epidermal growth factor receptor mediated by c-Src phosphorylation of RasGRP3. Stope, M.B., Vom Dorp, F., Szatkowski, D., Böhm, A., Keiper, M., Nolte, J., Oude Weernink, P.A., Rosskopf, D., Evellin, S., Jakobs, K.H., Schmidt, M. Mol. Cell. Biol. (2004)
- The EGF receptor: a nexus for trafficking and signaling. Carpenter, G. Bioessays (2000)
- A novel human nucleolar protein, Nop132, binds to the G proteins, RRAG A/C/D. Sekiguchi, T., Todaka, Y., Wang, Y., Hirose, E., Nakashima, N., Nishimoto, T. J. Biol. Chem. (2004)
- Signal transduction elements of TC21, an oncogenic member of the R-Ras subfamily of GTP-binding proteins. Movilla, N., Crespo, P., Bustelo, X.R. Oncogene (1999)
- Identification of the guanine nucleotide dissociation stimulator for Ral as a putative effector molecule of R-ras, H-ras, K-ras, and Rap. Spaargaren, M., Bischoff, J.R. Proc. Natl. Acad. Sci. U.S.A. (1994)
- KappaB-Ras binds to the unique insert within the ankyrin repeat domain of IkappaBbeta and regulates cytoplasmic retention of IkappaBbeta x NF-kappaB complexes. Chen, Y., Wu, J., Ghosh, G. J. Biol. Chem. (2003)
- Identification of a novel Ras-regulated proapoptotic pathway. Khokhlatchev, A., Rabizadeh, S., Xavier, R., Nedwidek, M., Chen, T., Zhang, X.F., Seed, B., Avruch, J. Curr. Biol. (2002)
- cDNA cloning of a human RAB26-related gene encoding a Ras-like GTP-binding protein on chromosome 16p13.3 region. Seki, N., Yoshikawa, T., Hattori, A., Miyajima, N., Muramatsu, M., Saito, T. J. Hum. Genet. (2000)
- Rig is a novel Ras-related protein and potential neural tumor suppressor. Ellis, C.A., Vos, M.D., Howell, H., Vallecorsa, T., Fults, D.W., Clark, G.J. Proc. Natl. Acad. Sci. U.S.A. (2002)
- Use of a native affinity ligand for the detection of G proteins by capillary isoelectric focusing with laser-induced fluorescence detection. Cunliffe, J.M., Liu, Z., Pawliszyn, J., Kennedy, R.T. Electrophoresis (2004)
- Evidence for expression of a Ras-like and a stage specific GTP binding homologous protein by Plasmodium falciparum. Thélu, J., Bracchi, V., Burnod, J., Ambroise-Thomas, P. Cell. Signal. (1994)