The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Gene Review

SNORA73B  -  small nucleolar RNA, H/ACA box 73B

Homo sapiens

Synonyms: 105A, E1c, RNU105A, RNU17B, U17B
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on RNU105A

  • The E1c isoform predominated in drug-selected MCF-7 cell lines and was translated more efficiently in MCF-7 cells than the E1a isoform [1].
  • Chemiluminescent assays measured urinary LH and FSH, as well as metabolites of estradiol [estrone conjugates (E1c)] and progesterone [pregnanediol glucuronide (Pdg)] [2].
  • Women collected daily, first morning voided urine for measurement of estradiol and progesterone metabolite excretion, estrone conjugates (E1c), and pregnanediol glucuronide (Pdg), respectively, throughout the cycle of study [3].
  • E1c and Pdg were integrated throughout the cycle using the trapezoidal rule, and correlations were sought between deviation from expected histology (based upon urinary hormones and LH surge) and integrated hormone values [3].
  • Hb E1c as an indicator for the presence of Hb AE phenotype in diabetic patients [4].

Biological context of RNU105A


Analytical, diagnostic and therapeutic context of RNU105A

  • Compared with heavier women, those with body mass index less than 25 kg/m2 had shorter cycles and higher total-cycle LH, FSH, and Pdg but not E1c [2].


  1. Novel 5' untranslated region variants of BCRP mRNA are differentially expressed in drug-selected cancer cells and in normal human tissues: implications for drug resistance, tissue-specific expression, and alternative promoter usage. Nakanishi, T., Bailey-Dell, K.J., Hassel, B.A., Shiozawa, K., Sullivan, D.M., Turner, J., Ross, D.D. Cancer Res. (2006) [Pubmed]
  2. Body size and ethnicity are associated with menstrual cycle alterations in women in the early menopausal transition: The Study of Women's Health across the Nation (SWAN) Daily Hormone Study. Santoro, N., Lasley, B., McConnell, D., Allsworth, J., Crawford, S., Gold, E.B., Finkelstein, J.S., Greendale, G.A., Kelsey, J., Korenman, S., Luborsky, J.L., Matthews, K., Midgley, R., Powell, L., Sabatine, J., Schocken, M., Sowers, M.F., Weiss, G. J. Clin. Endocrinol. Metab. (2004) [Pubmed]
  3. Luteal progesterone relates to histological endometrial maturation in fertile women. Santoro, N., Goldsmith, L.T., Heller, D., Illsley, N., McGovern, P., Molina, C., Peters, S., Skurnick, J.H., Forst, C., Weiss, G. J. Clin. Endocrinol. Metab. (2000) [Pubmed]
  4. Hb E1c as an indicator for the presence of Hb AE phenotype in diabetic patients. Wong, S.C., Aw, T.C. Clin. Chem. (1998) [Pubmed]
  5. Association between interleukin-18 gene polymorphism 105A/C and asthma. Higa, S., Hirano, T., Mayumi, M., Hiraoka, M., Ohshima, Y., Nambu, M., Yamaguchi, E., Hizawa, N., Kondo, N., Matsui, E., Katada, Y., Miyatake, A., Kawase, I., Tanaka, T. Clin. Exp. Allergy (2003) [Pubmed]
  6. IL-18 gene polymorphisms affect IL-18 production capability by monocytes. Arimitsu, J., Hirano, T., Higa, S., Kawai, M., Naka, T., Ogata, A., Shima, Y., Fujimoto, M., Yamadori, T., Hagiwara, K., Ohgawara, T., Kuwabara, Y., Kawase, I., Tanaka, T. Biochem. Biophys. Res. Commun. (2006) [Pubmed]
WikiGenes - Universities