Disease relevance of Chemiluminescent Measurements

• A chemiluminescent assay for reverse transcriptase (RT) of the human immunodeficiency virus 1 was developed using biotin-labeled oligodeoxythymidylic acid (biotin oligo-dT) and digoxigenin-deoxyuridine triphosphate instead of tritiated thymidine triphosphate [1].
• Menadione-catalyzed O2- production by Escherichia coli cells: application of rapid chemiluminescent assay to antimicrobial susceptibility testing [2].
• Quantitative determination of tomato yellow leaf curl geminivirus DNA by chemiluminescent assay using digoxigenin-labeled probes [3].
• Evaluation of thyrotropin secretion before and after TRH by third generation chemiluminescent assay. Assessment of subclinical hyperthyroidism [4].
• A chemiluminescent assay for hepatitis-B surface antigen is described which used an isoluminol derivative as the label [5].

High impact information on Chemiluminescent Measurements

• Plasma GH concentrations were measured every 10 min for 24 h during both saline and rhIGF-I infusions using a sensitive chemiluminescent assay [6].
• Nitrate content was measured by chemiluminescent assay [7].
• Calibration of the chemiluminescent assay was conducted by developing a standard curve using known concentrations of PSA [8].
• Transduction efficiency of the lacZ gene was estimated histochemically by X-gal staining and quantitatively using a chemiluminescent assay [9].
• Tg was assayed by immunoradiometric assay or chemiluminescent assay in ultrasound-guided FNAB used for cytology [10].

Chemical compound and disease context of Chemiluminescent Measurements

• p-Iodophenol-enhanced luminol chemiluminescent assay applied to discrimination between acute lymphoblastic and minimally differentiated acute myeloid (FAB-M0) or acute megakaryoblastic (FAB-M7) leukemias [11].
• We studied the effect of bilirubin and hemolysis on the MEIA for troponin I and compared our assay with a newly available chemiluminescent assay (CLIA) for troponin I (Bayer Diagnostics, Tarrytown, NY) [12].

Biological context of Chemiluminescent Measurements

• We found that a chemiluminescent assay for alkaline phosphatase allows measurement of antigen levels of secreted alkaline phosphatase (SEAP) in vivo after intramuscular injection of a wide range of plasmid doses [13].
• The finding that butyrylcholinesterase is responsible for the hydrolysis of MPB in serum should serve as the basis for the development of a specific chemiluminescent assay for this enzyme [14].

Anatomical context of Chemiluminescent Measurements

• The effects of cetiedil and its analogue MR 16728 were examined on spontaneous acetylcholine release measured with a chemiluminescent assay using choline oxidase in a synaptosomal suspension obtained from Torpedo marmorata electric organ [15].
• Neutrophil O(-)(2)- generating capacity was assessed by a lucigenin-based chemiluminescent assay of NADPH oxidase activity [16].
• A chemiluminescent assay was used to continuously measure the soluble AChE concentration from tissue punches of the substantia nigra [17].
• A chemiluminescent assay was used to measure generation of excited oxygen species by peripheral blood monocytes obtained from normal controls (NC) and patients with rheumatoid arthritis (RA) [18].
• A highly sensitive chemiluminescent assay for glycerylphosphorylcholine in human seminal plasma [19].

Associations of Chemiluminescent Measurements with chemical compounds

• Lucigenin and linoleate enhanced chemiluminescent assay for superoxide dismutase activity [20].
• Chemiluminescent assays measured urinary LH and FSH, as well as metabolites of estradiol [estrone conjugates (E1c)] and progesterone [pregnanediol glucuronide (Pdg)] [21].
• Simultaneous determination of total IgE and allergen-specific IgE in serum by the MAST chemiluminescent assay system [22].
• We assessed a new strategy for thyroid-function testing that involves simultaneous measurement of free thyroxin and thyrotropin, both in singletons, with chemiluminescent assays [23].
• Peroxyoxalate chemiluminescent assay in aqueous solution with gamma-cyclodextrin [24].

Gene context of Chemiluminescent Measurements

• Reference ranges for two automated chemiluminescent assays for serum insulin-like growth factor I (IGF-I) and IGF-binding protein 3 (IGFBP-3) [25].
• IL-6 and PCT levels were measured in serum by chemiluminescent assay [26].
• The chemiluminescent assay for cTnI showed no detectable cTnI concentration in any specimen [27].
• CT-1 in extracted plasma specimens was measured with a competitive chemiluminescent assay [28].
• The transfected cells were dosed with known inducers of CYP3A4 and the levels of SPAP in the medium were subsequently measured using a chemiluminescent assay, as an indirect measure of CYP3A4 induction [29].

Analytical, diagnostic and therapeutic context of Chemiluminescent Measurements

• In addition, several patients with undetectable basal and detectable TRH-stimulated TSH values in the immunoradiometric assay had detectable basal TSH values in the chemiluminescent assay [30].
• We supplemented aliquots of drug-free serum with fosphenytoin and measured the phenytoin equivalent concentrations (reading a) using fluorescence polarization immunoassay and a chemiluminescent assay [31].
• They measured apparent digoxin and digitoxin concentrations using fluorescence polarization, microparticle enzyme immunoassay, and chemiluminescent assays for digitoxin [32].
• Bronchial provocation tests (BPT) with allergen extracts were performed in 82 children with asthma, and the results were compared with the chemiluminescent assay (CLA), the radio-allergo-sorbent-test (RAST) and skin prick test (SPT) [33].
• With the chemiluminescent assay it was possible to detect 0.5, 1, or 2 pg of target homologous DNA, using PS-3, ECL, or Renaissance (RE) reagents, respectively, while colorimetry had a detection limit of 5 pg [34].

References