Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

LHB - luteinizing hormone beta polypeptide

Bos taurus

Kaetzel, D.M. et al., Keri, R.A. et al., Landefeld, T. et al.

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High impact information on LHB

The proximal promoter of the bovine luteinizing hormone beta-subunit gene confers gonadotrope-specific expression and regulation by gonadotropin-releasing hormone, testosterone, and 17 beta-estradiol in transgenic mice [1].
Disruption of N-linked glycosylation of bovine luteinizing hormone beta-subunit by site-directed mutagenesis dramatically increases its intracellular stability but does not affect biological activity of the secreted heterodimer [2].
Luteinizing hormone beta-subunit mRNA amounts increase during the preovulatory surge of luteinizing hormone in the ewe: the highest levels are observed at the completion of the peak [3].

References

The proximal promoter of the bovine luteinizing hormone beta-subunit gene confers gonadotrope-specific expression and regulation by gonadotropin-releasing hormone, testosterone, and 17 beta-estradiol in transgenic mice. Keri, R.A., Wolfe, M.W., Saunders, T.L., Anderson, I., Kendall, S.K., Wagner, T., Yeung, J., Gorski, J., Nett, T.M., Camper, S.A. Mol. Endocrinol. (1994) [Pubmed]
Disruption of N-linked glycosylation of bovine luteinizing hormone beta-subunit by site-directed mutagenesis dramatically increases its intracellular stability but does not affect biological activity of the secreted heterodimer. Kaetzel, D.M., Virgin, J.B., Clay, C.M., Nilson, J.H. Mol. Endocrinol. (1989) [Pubmed]
Luteinizing hormone beta-subunit mRNA amounts increase during the preovulatory surge of luteinizing hormone in the ewe: the highest levels are observed at the completion of the peak. Landefeld, T., Maurer, R., Kepa, J. DNA (1985) [Pubmed]

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LHB	Canis lupus familiaris
lhb	Danio rerio
LHB	Homo sapiens
LOC100429401	Macaca mulatta
Lhb	Mus musculus
LHB	Pan troglodytes
Lhb	Rattus norvegicus
LOC100490615	Xenopus (Silurana) tropicalis

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