The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
Gene Review

dpi  -  protein L

Escherichia coli

 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of dpi

  • Our study indicates, that (1) Stx produced during edema disease does not cause SMC apoptosis 14-15 dpi; (2) SMCs undergo an array of changes from degeneration to necrosis [1].
  • Some strains of the anaerobic human commensal and pathogen Peptostreptococcus magnus bind human serum albumin (HSA), whereas other strains of this species express protein L, an immunoglobulin light chain-binding surface protein [2].
  • An Escherichia coli high level expression system was adapted for the production of large amounts of two Ig-binding protein L fragments comprising one and four B repeats, respectively [3].
  • 13Cbeta-1Hbeta dipolar couplings have been measured for 38 of 49 possible residues in the 63-amino-acid B1 domain of peptostreptococcal protein L in two aligning media and interpreted in the context of side-chain chi1 torsion angle dynamics [4].
 

High impact information on dpi

 

Analytical, diagnostic and therapeutic context of dpi

References

  1. Ultrastructure and DNA fragmentation analysis of arterioles in swine infected with Shiga toxin-producing Escherichia coli. Matise, I., Sirinarumitr, T., Bosworth, B.T., Moon, H.W. Adv. Exp. Med. Biol. (1999) [Pubmed]
  2. Protein PAB, a mosaic albumin-binding bacterial protein representing the first contemporary example of module shuffling. de Château, M., Björck, L. J. Biol. Chem. (1994) [Pubmed]
  3. Structure of peptostreptococcal protein L and identification of a repeated immunoglobulin light chain-binding domain. Kastern, W., Sjöbring, U., Björck, L. J. Biol. Chem. (1992) [Pubmed]
  4. Chi1 torsion angle dynamics in proteins from dipolar couplings. Mittermaier, A., Kay, L.E. J. Am. Chem. Soc. (2001) [Pubmed]
  5. Three-dimensional solution structure of an immunoglobulin light chain-binding domain of protein L. Comparison with the IgG-binding domains of protein G. Wikström, M., Drakenberg, T., Forsén, S., Sjöbring, U., Björck, L. Biochemistry (1994) [Pubmed]
  6. Cloning, expression and purification of Ppl-1, a kappa-chain binding protein, based upon protein L from Peptostreptococcus magnus. Bottomley, S.P., Beckingham, J.A., Murphy, J.P., Atkinson, M., Atkinson, T., Hinton, R.J., Gore, M.G. Bioseparation (1995) [Pubmed]
  7. Nucleotide sequence of the gene for peptostreptococcal protein L. Murphy, J.P., Trowern, A.R., Duggleby, C.J. DNA Seq. (1994) [Pubmed]
  8. Protein L, a bacterial immunoglobulin-binding protein and possible virulence determinant. Kastern, W., Holst, E., Nielsen, E., Sjöbring, U., Björck, L. Infect. Immun. (1990) [Pubmed]
  9. On the interaction between single chain Fv antibodies and bacterial immunoglobulin-binding proteins. Akerström, B., Nilson, B.H., Hoogenboom, H.R., Björck, L. J. Immunol. Methods (1994) [Pubmed]
  10. Amplified expression and large-scale purification of protein L'. Murphy, J.P., Atkinson, M., Trowern, A.R., Stevens, G.B., Atkinson, T., Duggleby, C.J., Hinton, R.J. Bioseparation (1996) [Pubmed]
  11. Recombinant proteins L and LG. Two new tools for purification of murine antibody fragments. Vola, R., Lombardi, A., Tarditi, L., Zaccolo, M., Neri, D., Björck, L., Mariani, M. Cell Biophys. (1994) [Pubmed]
 
WikiGenes - Universities