Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Gene Review:

vkg - viking

Drosophila melanogaster

Synonyms: 1209, 6072, CG16858, CT25584, Coll IValpha2, ...

De Cian, M.C. et al., Mével-Ninio, M. et al., Olofsson, B. et al., Wilk, R. et al., Yasothornsrikul, S. et al.

De Cian, Bailly, Morales, Strub, Van Dorsselaer, Lallier,

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on vkg

The ovo transcript encodes a protein of at least 1209 amino acids with four zinc fingers, suggesting that ovo might be a transcription factor required for female germ line maintenance and gametogenesis [1].
In the absence of hemocytes migrating adjacent to the developing VNC, the extracellular matrix components Collagen IV, Viking and Peroxidasin are not deposited around this tissue [2].
The expression of several additional interactors--viking (vkg), Cg25, and laminin-alpha (LanA)-is affected only in a nonautonomous manner [3].
In early development, viking and DCg1 are transcribed in the same tissue-specific pattern, primarily in the hemocytes and fat body cells [4].
A complete 1209 kb cDNA has been sequenced from the trophosome and identified as a putative alpha-CA based on BLAST analysis and the similarities of total deduced amino-acid sequence with those from the GenBank database [5].

References

The ovo gene of Drosophila encodes a zinc finger protein required for female germ line development. Mével-Ninio, M., Terracol, R., Kafatos, F.C. EMBO J. (1991) [Pubmed]
Condensation of the central nervous system in embryonic Drosophila is inhibited by blocking hemocyte migration or neural activity. Olofsson, B., Page, D.T. Dev. Biol. (2005) [Pubmed]
Dose-sensitive autosomal modifiers identify candidate genes for tissue autonomous and tissue nonautonomous regulation by the Drosophila nuclear zinc-finger protein, hindsight. Wilk, R., Pickup, A.T., Hamilton, J.K., Reed, B.H., Lipshitz, H.D. Genetics (2004) [Pubmed]
viking: identification and characterization of a second type IV collagen in Drosophila. Yasothornsrikul, S., Davis, W.J., Cramer, G., Kimbrell, D.A., Dearolf, C.R. Gene (1997) [Pubmed]
Characterization of carbonic anhydrases from Riftia pachyptila, a symbiotic invertebrate from deep-sea hydrothermal vents. De Cian, M.C., Bailly, X., Morales, J., Strub, J.M., Van Dorsselaer, A., Lallier, F.H. Proteins (2003) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

Editor

Share