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Gene Review

birc5a  -  baculoviral IAP repeat containing 5a

Danio rerio

Synonyms: SO:0000704, bir5a, survivin
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High impact information on birc5a


Biological context of birc5a

  • Contrary to other members that directly interact with caspases and inhibit apoptosis, Survivin is believed to have both antiapoptotic and proliferative functions [1].
  • We show that the genomes of X. laevis, X. tropicalis, Zebrafish, fugu pufferfish, and rainbow trout encode two different Survivin genes (Su1 and Su2), contrary to mammalian genomes, which encode a single one [1].


  1. Survivin increased vascular development during Xenopus ontogenesis. Du Pasquier, D., Phung, A.C., Ymlahi-Ouazzani, Q., Sinzelle, L., Ballagny, C., Bronchain, O., Du Pasquier, L., Mazabraud, A. Differentiation (2006) [Pubmed]
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