Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

NME4 - NME/NM23 nucleoside diphosphate kinase 4

Gallus gallus

Synonyms: MNDPK, RAB11FIP3

Erecińska, M. et al., Islam, K. et al., Wilson, D.F. et al.

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High impact information on MNDPK

In this study, synthesis of phosphoenolpyruvate by guinea pig liver mitochondria was studied under conditions for which the only source of GTP was extramitochondrial ATP via adenine nucleotide translocase and nucleoside diphosphate kinase (the mitochondria were treated with rotenone, oligomycin, uncoupler, and fluorocitrate) [1].
Mitochondria isolated from these sources also contain nucleoside diphosphate kinase, malate dehydrogenase, and glutamate dehydrogenase or 3-OH-butyrate dehydrogenase [2].
The results show that nucleoside diphosphate kinase is not required for CTP-induced microtubule assembly, and suggest that CTP directly effects microtubule assembly [3].
Microtubules and nucleoside diphosphate kinase. Comparison of kinetics of GTP- and CTP-induced assembly [3].

References

Relationship of the intra- and extramitochondrial adenine nucleotide ratios during synthesis of phosphoenolpyruvate using extramitochondrial ATP. Erecińska, M., Wilson, D.F. J. Biol. Chem. (1984) [Pubmed]
Evaluation of the relationship between the intra- and extramitochondrial [ATP]/[ADP] ratios using phosphoenolpyruvate carboxykinase. Wilson, D.F., Erecińska, M., Schramm, V.L. J. Biol. Chem. (1983) [Pubmed]
Microtubules and nucleoside diphosphate kinase. Comparison of kinetics of GTP- and CTP-induced assembly. Islam, K., Burns, R.G. Biochem. J. (1985) [Pubmed]

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NDPK2	Arabidopsis thaliana
NME3	Bos taurus
NME3	Canis lupus familiaris
nme3	Danio rerio
NME3	Homo sapiens
LOC722479	Macaca mulatta
Nme3	Mus musculus
Os12g0548300	Oryza sativa Japonica Group
NME3	Pan troglodytes
Nme3	Rattus norvegicus
nme3	Xenopus (Silurana) tropicalis

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