The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Links

 

Gene Review

BFSP1  -  beaded filament structural protein 1,...

Gallus gallus

 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of BFSP1

  • I cloned and sequenced a full-length chicken lens cDNA encoding filensin, also known as CP95 (Ireland, M. and Maisel, H. (1989) Lens and Eye Toxicity Research 6, 623-638) [1].
 

High impact information on BFSP1

 

Associations of BFSP1 with chemical compounds

  • Filensin, a 100 kDa, membrane-associated, cytoskeletal protein, is uniquely expressed in the lens fiber cell (Merdes, A., Brunkener, M., Horstmann, H., and Georgatos, S. D. (1991) J. Cell Biol. 115, 397-410) [1].
  • The major population of the library consisted of cDNAs encoding delta-crystallin (about 35% of the recombinants) and other crystallins (alpha A-, alpha B-, beta A3/A1-, beta B1-, beta B2-), as well as cytoskeletal proteins (CP49, CP95), and membrane protein (MP28) [2].
 

Regulatory relationships of BFSP1

  • Finally, TGF-alpha treatment induced increased expression of the beaded filament protein filensin when compared with control cells [3].
 

Other interactions of BFSP1

  • Filensin expression was increased further when cells were costimulated with TGF-alpha and cAMP analogs [3].
 

Analytical, diagnostic and therapeutic context of BFSP1

  • Embryonic chicken filensin migrated in SDS-PAGE as a triplet of 102, 105 and 109 kDa, while rooster filensin migrated as a 105 and 109 kDa doublet [1].
  • ELISA assays quantified the effects of TGFalpha on filensin expression [4].

References

 
WikiGenes - Universities