The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

NTRK3  -  neurotrophic tyrosine kinase, receptor,...

Gallus gallus

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on NTRK3


Other interactions of NTRK3

  • In situ hybridization revealed that mRNA for the full-length (catalytic) NT-3 receptor, TrkC, was present in, and limited to, the neural plate (including the neural folds) coincident with its formation [4].
  • During chicken embryonic and early postnatal brain development, expression of full-length TrkB and TrkC proteins preceded the onset of the truncated forms of these receptors [2].

Analytical, diagnostic and therapeutic context of NTRK3

  • TrkC receptor isoforms have been identified by cDNA cloning and RT-PCR analysis of embryonic chick brain RNA [5].


  1. Inhibition of the NT-3 receptor TrkC, early in chick embryogenesis, results in severe reductions in multiple neuronal subpopulations in the dorsal root ganglia. Lefcort, F., Clary, D.O., Rusoff, A.C., Reichardt, L.F. J. Neurosci. (1996) [Pubmed]
  2. Regulation of neurotrophin receptor expression during embryonic and postnatal development. Escandón, E., Soppet, D., Rosenthal, A., Mendoza-Ramírez, J.L., Szönyi, E., Burton, L.E., Henderson, C.E., Parada, L.F., Nikolics, K. J. Neurosci. (1994) [Pubmed]
  3. Trk C receptor signaling regulates cardiac myocyte proliferation during early heart development in vivo. Lin, M.I., Das, I., Schwartz, G.M., Tsoulfas, P., Mikawa, T., Hempstead, B.L. Dev. Biol. (2000) [Pubmed]
  4. Neurotrophin-3 increases neurite outgrowth and apoptosis in explants of the chicken neural plate. Li, R., Bernd, P. Dev. Neurosci. (1999) [Pubmed]
  5. Isoforms of the avian TrkC receptor: a novel kinase insertion dissociates transformation and process outgrowth from survival. Garner, A.S., Large, T.H. Neuron (1994) [Pubmed]
WikiGenes - Universities