High impact information on P11

• Interestingly the N-terminal acetyl group of p36 forms a functional part of the p11 binding site [1].
• This sequence shows that the v-mil gene is fused to the gag gene giving rise to a fused polyprotein of 98 000 daltons: 515 amino acids at the amino terminus would correspond to p10, p19, p27 and part of p12 determinants, 347 amino acids at the carboxy terminus correspond to the v-mil specific sequence [2].
• By P11, Vim staining was faint, whereas GFAP staining gained in intensity, indicating the presence of mature astrocytes [3].
• The hemagglutinin of Q1/95 and P11/ 94B parent stock and derivative AIVs had an identical proteolytic cleavage site of.... Pro-Gln-Arg-Lys-Arg-Lys-Thr-Arg-Gly, consistent with AIVs of high pathogenicity [4].
• Flow cytometric analysis of the hybridomas secreting the P11 and P66 mAb showed expression of surface IgM and IgG, respectively [5].

Associations of P11 with chemical compounds

• Here we have characterized the p11 binding site on p36 by fluorescence spectroscopy using porcine p36 labelled at cysteine 8 with the fluorophore Prodan (6-proprionyl-2-dimethylamino-naphthalene) [1].

Analytical, diagnostic and therapeutic context of P11

• Western blot analysis under reducing conditions showed that mAb P11 recognized a sporozoite protein of 43 kDa [5].

References