Disease relevance of cvpA

• Colicin V production by clinical isolates of Escherichia coli [1].

High impact information on cvpA

• In contrast, serum resistance was not significantly associated with antibiotic resistance (whether transmissible or not), with colicinogeny in general, or with colicin V production in particular [2].
• Strains of Escherichia coli isolated from random fecal samples, urines of hospitalized and nonhospitalized patients who had urinary tract infections, and blood of patients with septicemia were examined for colicin V production [1].
• Characterization of a purF operon mutation which affects colicin V production [3].
• A mini-Tn10-kan insertion mutation identified a gene in the chromosome of Escherichia coli required for colicin V production from plasmid pColV-K30 [3].
• Test organisms consisted of two virulent E. coli isolates, one avirulent isolate, and one laboratory-derived mutant of the avirulent isolate carrying a recombinant plasmid coding for Colicin V production [4].

Biological context of cvpA

• Week 1 isolates from 52 definable episodes were tested for hemagglutination, hybridization with gene sequences from the pil and pap operons, in vitro adherence to catheter material, binding of 125I-labeled Tamm-Horsfall protein, hemolysin and colicin V production, and serum resistance [5].
• This characteristic associated with minor properties like surface proteins type, colicin V production and virulence in mice made these 16,078 E. coli isolates from 4 animal species, good candidates for the same clonal grouping [6].
• Non-association of macrophage phagocytosis and oxidant stimulation with complement resistance and colicin V production by avian Escherichia coli [7].
• In the case of three strains the increase of LD50 values, which means the decrease of virulence, resulted in the loss of colicin V production and the loss of Col V plasmid [8].

Associations of cvpA with chemical compounds

• Although colicin V production was much more frequently associated with aerobactin production than other colicins, colicin V was only produced by 26% of aerobactin excreters [9].

References