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Gene Review

Ppa1  -  pyrophosphatase (inorganic) 1

Mus musculus

Synonyms: 2010317E03Rik, Inorganic pyrophosphatase, PPase, Pp, Pyp, ...
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Disease relevance of Ppa1

  • The causative agent of tuberculosis, Mycobacterium tuberculosis, contains a well conserved copy of PPase [1].

High impact information on Ppa1


Biological context of Ppa1


  1. Analysis of stress- and host cell-induced expression of the Mycobacterium tuberculosis inorganic pyrophosphatase. Triccas, J.A., Gicquel, B. BMC Microbiol. (2001) [Pubmed]
  2. Phosphate-induced vascular calcification: role of pyrophosphate and osteopontin. Lomashvili, K.A., Cobbs, S., Hennigar, R.A., Hardcastle, K.I., O'Neill, W.C. J. Am. Soc. Nephrol. (2004) [Pubmed]
  3. CFTR chloride channel activation by genistein: the role of serine/threonine protein phosphatases. Reenstra, W.W., Yurko-Mauro, K., Dam, A., Raman, S., Shorten, S. Am. J. Physiol. (1996) [Pubmed]
  4. Circadian rhythmometric analysis of hepatic phosphohydrolases with special reference to glucose-6-phosphatase and inorganic pyrophosphatase. Gupta, G.S., Sodhi, J., Gupta, V.P. Indian J. Biochem. Biophys. (1994) [Pubmed]
  5. Hysteretic behavior of the hepatic microsomal glucose-6-phosphatase system. Foster, J.D., Nelson, K.L., Sukalski, K.A., Lucius, R.W., Nordlie, R.C. Biochim. Biophys. Acta (1991) [Pubmed]
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