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Gene Review:

GPX1 - phospholipid hydroperoxide glutathione...

Arabidopsis thaliana

Synonyms: ATGPX1, F13D4.40, F13D4_40, GLUTATHIONE PEROXIDASE 1, glutathione peroxidase 1

Navabpour, S. et al., Iqbal, A. et al., Nutricati, E. et al., Miao, Y. et al., Sugimoto, M. et al.

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Disease relevance of ATGPX1

Four mature GPX isoenzymes with different subcellular distributions, AtGPX1, -2, -5 and -6, were overexpressed in Escherichia coli and characterized [1].

High impact information on ATGPX1

An Arabidopsis glutathione peroxidase functions as both a redox transducer and a scavenger in abscisic Acid and drought stress responses [2].
However, one gene, encoding a lipid hydroperoxide-dependent glutathione peroxidase, showed increased expression in the protected tissue, which may indicate a role for this enzyme in the protection of plant tissue from oxidative stress [3].
AtGSTF9 showed activity towards benzyl isothiocyanate (BITC) and an activity as glutathione peroxidase with cumene hydroperoxide (CumHPO) [4].
Molecular cloning and characterization of a cDNA encoding putative phospholipid hydroperoxide glutathione peroxidase from spinach [5].

References

Hydroperoxide reduction by thioredoxin-specific glutathione peroxidase isoenzymes of Arabidopsis thaliana. Iqbal, A., Yabuta, Y., Takeda, T., Nakano, Y., Shigeoka, S. FEBS J. (2006) [Pubmed]
An Arabidopsis glutathione peroxidase functions as both a redox transducer and a scavenger in abscisic Acid and drought stress responses. Miao, Y., Lv, D., Wang, P., Wang, X.C., Chen, J., Miao, C., Song, C.P. Plant Cell (2006) [Pubmed]
Expression of senescence-enhanced genes in response to oxidative stress. Navabpour, S., Morris, K., Allen, R., Harrison, E., A-H-Mackerness, S., Buchanan-Wollaston, V. J. Exp. Bot. (2003) [Pubmed]
Characterization of two Arabidopsis thaliana glutathione S-transferases. Nutricati, E., Miceli, A., Blando, F., De Bellis, L. Plant Cell Rep. (2006) [Pubmed]
Molecular cloning and characterization of a cDNA encoding putative phospholipid hydroperoxide glutathione peroxidase from spinach. Sugimoto, M., Furui, S., Suzuki, Y. Biosci. Biotechnol. Biochem. (1997) [Pubmed]

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GPX7	Arabidopsis thaliana
GPX4	Bos taurus
R03G5.5	Caenorhabditis elegans
T09A12.2	Caenorhabditis elegans
gpx4b	Danio rerio
GPX4	Homo sapiens
GPX4	Macaca mulatta
Gpx4	Mus musculus
Gpx4	Rattus norvegicus
GPX2	Saccharomyces cerevisiae S288c
gpx4	Xenopus (Silurana) tropicalis

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