Gene Review:
MUR1 - GDP-mannose 4,6 dehydratase 2
Arabidopsis thaliana
Synonyms:
6-DEHYDRATASE, 6-DEHYDRATASE 2, GDP-D-MANNOSE-4, GDP-D-MANNOSE-4,6-DEHYDRATASE 2, GMD2, ...
- A bifunctional epimerase-reductase acts downstream of the MUR1 gene product and completes the de novo synthesis of GDP-L-fucose in Arabidopsis. Bonin, C.P., Reiter, W.D. Plant J. (2000)
- Mutants of Arabidopsis thaliana with altered cell wall polysaccharide composition. Reiter, W.D., Chapple, C., Somerville, C.R. Plant J. (1997)
- Requirement of borate cross-linking of cell wall rhamnogalacturonan II for Arabidopsis growth. O'Neill, M.A., Eberhard, S., Albersheim, P., Darvill, A.G. Science (2001)
- Substitution of L-fucose by L-galactose in cell walls of Arabidopsis mur1. Zablackis, E., York, W.S., Pauly, M., Hantus, S., Reiter, W.D., Chapple, C.C., Albersheim, P., Darvill, A. Science (1996)
- The mur2 mutant of Arabidopsis thaliana lacks fucosylated xyloglucan because of a lesion in fucosyltransferase AtFUT1. Vanzin, G.F., Madson, M., Carpita, N.C., Raikhel, N.V., Keegstra, K., Reiter, W.D. Proc. Natl. Acad. Sci. U.S.A. (2002)
- The MUR1 gene of Arabidopsis thaliana encodes an isoform of GDP-D-mannose-4,6-dehydratase, catalyzing the first step in the de novo synthesis of GDP-L-fucose. Bonin, C.P., Potter, I., Vanzin, G.F., Reiter, W.D. Proc. Natl. Acad. Sci. U.S.A. (1997)
- Fucosylated arabinogalactan-proteins are required for full root cell elongation in arabidopsis. van Hengel, A.J., Roberts, K. Plant J. (2002)
- Structure of the MUR1 GDP-mannose 4,6-dehydratase from Arabidopsis thaliana: implications for ligand binding and specificity. Mulichak, A.M., Bonin, C.P., Reiter, W.D., Garavito, R.M. Biochemistry (2002)
- Interaction of GDP-4-keto-6-deoxymannose-3,5-epimerase-4-reductase with GDP-mannose-4,6-dehydratase stabilizes the enzyme activity for formation of GDP-fucose from GDP-mannose. Nakayama, K., Maeda, Y., Jigami, Y. Glycobiology (2003)