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Gene Review:

PAD2 - proteasome alpha subunit D2

Arabidopsis thaliana

Synonyms: 20S PROTEASOME SUBUNIT PAD2, K2A18.22, K2A18_22

Parisy, V. et al., Roetschi, A. et al.

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High impact information on PAD2

Surprisingly, in both pathosystems, the disease susceptibility of pad2-1 was not caused by the camalexin deficiency, suggesting additional roles of PAD2 in disease resistance [1].
Identification of PAD2 as a gamma-glutamylcysteine synthetase highlights the importance of glutathione in disease resistance of Arabidopsis [1].
Characterization of an Arabidopsis-Phytophthora pathosystem: resistance requires a functional PAD2 gene and is independent of salicylic acid, ethylene and jasmonic acid signalling [2].
However, pad2, a mutant with reduced production of the phytoalexin camalexin, was hyper-susceptible [2].

References

Identification of PAD2 as a gamma-glutamylcysteine synthetase highlights the importance of glutathione in disease resistance of Arabidopsis. Parisy, V., Poinssot, B., Owsianowski, L., Buchala, A., Glazebrook, J., Mauch, F. Plant J. (2007) [Pubmed]
Characterization of an Arabidopsis-Phytophthora pathosystem: resistance requires a functional PAD2 gene and is independent of salicylic acid, ethylene and jasmonic acid signalling. Roetschi, A., Si-Ammour, A., Belbahri, L., Mauch, F., Mauch-Mani, B. Plant J. (2001) [Pubmed]

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AgaP_AGAP005423	Anopheles gambiae str. PEST
PAD1	Arabidopsis thaliana
AGOS_AAR012C	Ashbya gossypii ATCC 10895
PSMA8	Bos taurus
PSMA8	Canis lupus familiaris
psma8	Danio rerio
Prosalpha4	Drosophila melanogaster
Prosalpha4T1	Drosophila melanogaster
PSMA8	Homo sapiens
KLLA0B11836g	Kluyveromyces lactis NRRL Y-1140
LOC719914	Macaca mulatta
MGG_06472	Magnaporthe oryzae 70-15
Psma8	Mus musculus
NCU06440	Neurospora crassa OR74A
Os08g0548900	Oryza sativa Japonica Group
Os09g0538200	Oryza sativa Japonica Group
PSMA8	Pan troglodytes
Psma8	Rattus norvegicus
PRE6	Saccharomyces cerevisiae S288c
pre6	Schizosaccharomyces pombe 972h-

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