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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

GSR2  -  glutamine synthetase

Arabidopsis thaliana

Synonyms: ATGSR2, F15E12.14, F15E12_14, GLN1;2, GLUTAMINE SYNTHETASE, ...
 
 
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High impact information on ATGSR2

  • GLN1;2 was the only isoenzyme significantly up-regulated by ammonium, which correlated with the rapid increase in total GS1 protein [1].
  • GLN1;2 was localized in the vasculature and exhibited low affinities to ammonium (Km = 2450 +/- 150 microm) and glutamate (Km = 3.8 +/- 0.2 mm) [1].
  • Other markers of natural senescence, SAG12, SAG19, MT1 (metallothionein), and Atgsr2 (glutamine synthetase), did not show enhanced transcript accumulation [2].
  • Four distinct GS cDNA clones, lambda Atgsl1, lambda Atgsr1, lambda Atgsr2 and lambda Atkb6 were isolated and characterized [3].

References

  1. Kinetic properties and ammonium-dependent regulation of cytosolic isoenzymes of glutamine synthetase in Arabidopsis. Ishiyama, K., Inoue, E., Watanabe-Takahashi, A., Obara, M., Yamaya, T., Takahashi, H. J. Biol. Chem. (2004) [Pubmed]
  2. Senescence-associated gene expression during ozone-induced leaf senescence in Arabidopsis. Miller, J.D., Arteca, R.N., Pell, E.J. Plant Physiol. (1999) [Pubmed]
  3. The glutamine synthetase gene family of Arabidopsis thaliana: light-regulation and differential expression in leaves, roots and seeds. Peterman, T.K., Goodman, H.M. Mol. Gen. Genet. (1991) [Pubmed]
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