Gene Review:
SKI2 - SKI complex RNA helicase subunit SKI2
Saccharomyces cerevisiae S288c
Synonyms:
Antiviral helicase SKI2, L8084.17, Superkiller protein 2, YLR398C
- Ski6p is a homolog of RNA-processing enzymes that affects translation of non-poly(A) mRNAs and 60S ribosomal subunit biogenesis. Benard, L., Carroll, K., Valle, R.C., Wickner, R.B. Mol. Cell. Biol. (1998)
- The 3' to 5' degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3' to 5' exonucleases of the exosome complex. Anderson, J.S., Parker, R.P. EMBO J. (1998)
- 3' poly(A) is dispensable for translation. Searfoss, A.M., Wickner, R.B. Proc. Natl. Acad. Sci. U.S.A. (2000)
- Linking the 3' poly(A) tail to the subunit joining step of translation initiation: relations of Pab1p, eukaryotic translation initiation factor 5b (Fun12p), and Ski2p-Slh1p. Searfoss, A., Dever, T.E., Wickner, R. Mol. Cell. Biol. (2001)
- Saccharomyces cerevisiae RAI1 (YGL246c) is homologous to human DOM3Z and encodes a protein that binds the nuclear exoribonuclease Rat1p. Xue, Y., Bai, X., Lee, I., Kallstrom, G., Ho, J., Brown, J., Stevens, A., Johnson, A.W. Mol. Cell. Biol. (2000)
- Decoying the cap- mRNA degradation system by a double-stranded RNA virus and poly(A)- mRNA surveillance by a yeast antiviral system. Masison, D.C., Blanc, A., Ribas, J.C., Carroll, K., Sonenberg, N., Wickner, R.B. Mol. Cell. Biol. (1995)
- Domain interactions within the Ski2/3/8 complex and between the Ski complex and Ski7p. Wang, L., Lewis, M.S., Johnson, A.W. RNA (2005)
- Identification of gene encoding a putative RNA-helicase, homologous to SKI2, in chromosome VII of Saccharomyces cerevisiae. Martegani, E., Vanoni, M., Mauri, I., Rudoni, S., Saliola, M., Alberghina, L. Yeast (1997)
- Mak21p of Saccharomyces cerevisiae, a homolog of human CAATT-binding protein, is essential for 60 S ribosomal subunit biogenesis. Edskes, H.K., Ohtake, Y., Wickner, R.B. J. Biol. Chem. (1998)
- Synthetic lethality of sep1 (xrn1) ski2 and sep1 (xrn1) ski3 mutants of Saccharomyces cerevisiae is independent of killer virus and suggests a general role for these genes in translation control. Johnson, A.W., Kolodner, R.D. Mol. Cell. Biol. (1995)
- The structure of Ski8p, a protein regulating mRNA degradation: Implications for WD protein structure. Madrona, A.Y., Wilson, D.K. Protein Sci. (2004)
- Evidence that the SKI antiviral system of Saccharomyces cerevisiae acts by blocking expression of viral mRNA. Widner, W.R., Wickner, R.B. Mol. Cell. Biol. (1993)