Gene Review:
XRN1 - Xrn1p
Saccharomyces cerevisiae S288c
Synonyms:
5'-3' exoribonuclease 1, DNA strand transfer protein beta, DST2, G1645, KAR(-)-enhancing mutation protein, ...
- Deletion of OSH3 gene confers resistance against ISP-1 in Saccharomyces cerevisiae. Yano, T., Inukai, M., Isono, F. Biochem. Biophys. Res. Commun. (2004)
- Lithium toxicity in yeast is due to the inhibition of RNA processing enzymes. Dichtl, B., Stevens, A., Tollervey, D. EMBO J. (1997)
- Periodic gene expression program of the fission yeast cell cycle. Rustici, G., Mata, J., Kivinen, K., Lió, P., Penkett, C.J., Burns, G., Hayles, J., Brazma, A., Nurse, P., Bähler, J. Nat. Genet. (2004)
- The yeast KEM1 gene encodes a nuclease specific for G4 tetraplex DNA: implication of in vivo functions for this novel DNA structure. Liu, Z., Gilbert, W. Cell (1994)
- Activated transcription independent of the RNA polymerase II holoenzyme in budding yeast. McNeil, J.B., Agah, H., Bentley, D. Genes Dev. (1998)
- Deadenylation of the unstable mRNA encoded by the yeast MFA2 gene leads to decapping followed by 5'-->3' digestion of the transcript. Muhlrad, D., Decker, C.J., Parker, R. Genes Dev. (1994)
- Isolation and characterization of RAT1: an essential gene of Saccharomyces cerevisiae required for the efficient nucleocytoplasmic trafficking of mRNA. Amberg, D.C., Goldstein, A.L., Cole, C.N. Genes Dev. (1992)
- An essential yeast gene with homology to the exonuclease-encoding XRN1/KEM1 gene also encodes a protein with exoribonuclease activity. Kenna, M., Stevens, A., McCammon, M., Douglas, M.G. Mol. Cell. Biol. (1993)
- Structure of the yeast TAP1 protein: dependence of transcription activation on the DNA context of the target gene. Aldrich, T.L., Di Segni, G., McConaughy, B.L., Keen, N.J., Whelen, S., Hall, B.D. Mol. Cell. Biol. (1993)
- ROK1, a high-copy-number plasmid suppressor of kem1, encodes a putative ATP-dependent RNA helicase in Saccharomyces cerevisiae. Song, Y., Kim, S., Kim, J. Gene (1995)
- The sequence of an 11.1 kb fragment on the left arm of Saccharomyces cerevisiae chromosome VII reveals six open reading frames including NSP49, KEM1 and four putative new genes. Bertani, I., Coglievina, M., Zaccaria, P., Klima, R., Bruschi, C.V. Yeast (1995)
- Identification of an exoribonuclease homolog, CaKEM1/CaXRN1, in Candida albicans and its characterization in filamentous growth. An, H.S., Lee, K.H., Kim, J. FEMS Microbiol. Lett. (2004)
- Regulation and intracellular localization of Saccharomyces cerevisiae strand exchange protein 1 (Sep1/Xrn1/Kem1), a multifunctional exonuclease. Heyer, W.D., Johnson, A.W., Reinhart, U., Kolodner, R.D. Mol. Cell. Biol. (1995)
- Turnover mechanisms of the stable yeast PGK1 mRNA. Muhlrad, D., Decker, C.J., Parker, R. Mol. Cell. Biol. (1995)
- A role of Sep1 (= Kem1, Xrn1) as a microtubule-associated protein in Saccharomyces cerevisiae. Interthal, H., Bellocq, C., Bähler, J., Bashkirov, V.I., Edelstein, S., Heyer, W.D. EMBO J. (1995)
- Glucose-dependent turnover of the mRNAs encoding succinate dehydrogenase peptides in Saccharomyces cerevisiae: sequence elements in the 5' untranslated region of the Ip mRNA play a dominant role. Cereghino, G.P., Atencio, D.P., Saghbini, M., Beiner, J., Scheffler, I.E. Mol. Biol. Cell (1995)
- Sodium-induced GCN4 expression controls the accumulation of the 5' to 3' RNA degradation inhibitor, 3'-phosphoadenosine 5'-phosphate. Todeschini, A.L., Condon, C., Bénard, L. J. Biol. Chem. (2006)
- Inhibition of mRNA turnover in yeast by an xrn1 mutation enhances the requirement for eIF4E binding to eIF4G and for proper capping of transcripts by Ceg1p. Brown, J.T., Yang, X., Johnson, A.W. Genetics (2000)
- Two-hybrid cloning and characterization of OSH3, a yeast oxysterol-binding protein homolog. Park, Y.U., Hwang, O., Kim, J. Biochem. Biophys. Res. Commun. (2002)
- Saccharomyces cerevisiae proteins involved in hybrid DNA formation in vitro. Heyer, W.D., Johnson, A.W., Norris, D.N., Tishkoff, D., Kolodner, R.D. Biochimie (1991)
- A transcriptional pathway for cell separation in fission yeast. Bähler, J. Cell Cycle (2005)
- Molecular and genetic analysis of the gene encoding the Saccharomyces cerevisiae strand exchange protein Sep1. Tishkoff, D.X., Johnson, A.W., Kolodner, R.D. Mol. Cell. Biol. (1991)
- Synthetic lethality of sep1 (xrn1) ski2 and sep1 (xrn1) ski3 mutants of Saccharomyces cerevisiae is independent of killer virus and suggests a general role for these genes in translation control. Johnson, A.W., Kolodner, R.D. Mol. Cell. Biol. (1995)
- The Sep1 strand exchange protein from Saccharomyces cerevisiae promotes a paranemic joint between homologous DNA molecules. Chen, J., Kanaar, R., Cozzarelli, N.R. Genes Dev. (1994)
- Characterization of the interaction of Saccharomyces cerevisiae strand exchange protein 1 with DNA. Johnon, A.W., Kolodner, R.D. J. Biol. Chem. (1994)
- Disruption of the gene XRN1, coding for a 5'----3' exoribonuclease, restricts yeast cell growth. Larimer, F.W., Stevens, A. Gene (1990)