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Gene Review

ATG2  -  Atg2p

Saccharomyces cerevisiae S288c

Synonyms: APG2, AUT8, Autophagy-related protein 2, N1106, SPO72, ...
 
 
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High impact information on ATG2

  • We have identified and characterized a novel protein Apg2p essential for autophagy in yeast [1].
  • Apg2p localizes to some membranous structure distinct from any known organelle [1].
  • Apg2 localizes to the previously identified perivacuolar compartment that contains Apg9, the only characterized integral membrane protein that is required for autophagosome/Cvt vesicle formation [2].
  • In this study, we have identified a novel protein, termed Apg2, required for both the Cvt and autophagy pathways as well as the specific degradation of peroxisomes [2].
  • The majority of Cca1p-II and Cca1p-III, translated from ATG2 and ATG3, respectively, is in the cytosol but both are also located in the nucleus for processing precursors [3].
 

Biological context of ATG2

 

Anatomical context of ATG2

 

Associations of ATG2 with chemical compounds

 

Analytical, diagnostic and therapeutic context of ATG2

References

 
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