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Gene Review

TRP2  -  anthranilate synthase TRP2

Saccharomyces cerevisiae S288c

Synonyms: Anthranilate synthase component 1, Anthranilate synthase component I, YER090W
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High impact information on TRP2

  • The same effect was achieved by removing the competing enzyme anthranilate synthase, which is encoded by the TRP2 gene, from the transcriptional control [1].
  • The allelic situation of ARO7(c) being under general control instead of TRP2 resulted in severe growth defects when cells were starved for tryptophan [1].
  • The nucleotide sequence of TRP2 as well as that of TRP3 were determined [2].
  • RPL17B was mapped by CHEF and lambda clone grid hybridization blots to the right arm of chromosome V, linked to the TRP2 and RAD51 genes [3].
  • These studies were conducted in comparison with an earlier construction, pME554, which differs from plasmid pME559 in the expression of the TRP1 gene and which carries the TRP2 wild type instead of the TRP2fbr mutant allele [4].

Biological context of TRP2

  • The 9 base pair direct repeat (Hinnebusch, A.G., and Fink, G.R. (1983) J. Biol. Chem. 258, 5238-5247) and inverted repeats were identified in the 5'-flanking sequences of TRP2 and TRP3 [2].

Associations of TRP2 with chemical compounds


Other interactions of TRP2

  • The plasmid-borne genes TRP2 to TRP5 were expressed and regulated normally in the frame of the general control [6].

Analytical, diagnostic and therapeutic context of TRP2


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