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Gene Review

desA  -  fatty acid desaturase

Synechocystis sp. PCC 6803

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Disease relevance of desA


High impact information on desA


Anatomical context of desA


Associations of desA with chemical compounds

  • Rifampicin, chloramphenicol, and 3-(3, 4-dichlorophenyl)-1,1-dimethylurea completely blocked the induction of the expression of desA, desB, and desD [6].


  1. The primary signal in the biological perception of temperature: Pd-catalyzed hydrogenation of membrane lipids stimulated the expression of the desA gene in Synechocystis PCC6803. Vigh, L., Los, D.A., Horváth, I., Murata, N. Proc. Natl. Acad. Sci. U.S.A. (1993) [Pubmed]
  2. Identification of conserved domains in the delta 12 desaturases of cyanobacteria. Sakamoto, T., Wada, H., Nishida, I., Ohmori, M., Murata, N. Plant Mol. Biol. (1994) [Pubmed]
  3. Site-directed mutagenesis of histidine residues in the delta 12 acyl-lipid desaturase of Synechocystis. Avelange-Macherel, M.H., Macherel, D., Wada, H., Murata, N. FEBS Lett. (1995) [Pubmed]
  4. Targeted mutagenesis of acyl-lipid desaturases in Synechocystis: evidence for the important roles of polyunsaturated membrane lipids in growth, respiration and photosynthesis. Tasaka, Y., Gombos, Z., Nishiyama, Y., Mohanty, P., Ohba, T., Ohki, K., Murata, N. EMBO J. (1996) [Pubmed]
  5. Bioenergetic responses of Synechocystis 6803 fatty acid desaturase mutants at low temperatures. Dilley, R.A., Nishiyama, Y., Gombos, Z., Murata, N. J. Bioenerg. Biomembr. (2001) [Pubmed]
  6. Light-induced expression of fatty acid desaturase genes. Kis, M., Zsiros, O., Farkas, T., Wada, H., Nagy, F., Gombos, Z. Proc. Natl. Acad. Sci. U.S.A. (1998) [Pubmed]
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