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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Table of contents

About

Terms

 

Gene Review: 

CARTPT  -  CART prepropeptide

Homo sapiens

Synonyms: CART, Cocaine-and amphetamine-regulated transcript protein
 
 
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Disease relevance of CARTPT

 

High impact information on CARTPT

  • ATP-sensitive potassium channels were expressed in orexigenic neuropeptide Y/agouti-related protein (NPY/AgRP) and ghrelin-sensitive neurons and in anorexigenic cocaine-and-amphetamine regulated transcript (CART) neurons [3].
  • O2 consumption (VO2, ml/min, STPD), CO2 production (VCO2, ml/min, STPD) and respiratory quotient (RQ) measurements were made every 15 min using a Beckman Metabolic Measurement Cart [4].
  • Heart rate was continuously monitored by an ECG, and a Beckman Metabolic Cart analyzed ventilation (VE), breathing rate (f), and oxygen uptake (VO2) every minute [5].
 

Analytical, diagnostic and therapeutic context of CARTPT

  • Our objective was to determine the validity of the SensorMedics 2900 Metabolic Measurement Cart (SensorMedics Corp., Yorba Linda, CA) for use at pediatric ventilator volumes by designing an in vitro validation study [6].

References

  1. Assessment of oxygen-consumption by use of reverse Fick-principle and indirect calorimetry in critically Ill patients. Schneeweiss, B., Druml, W., Graninger, W., Grimm, G., Kleinberger, G., Lenz, K., Laggner, A. Clinical nutrition (Edinburgh, Scotland) (1989) [Pubmed]
  2. Hypothalamic neuropeptide systems and anticipatory weight change in Siberian hamsters. Adam, C.L., Mercer, J.G. Physiol. Behav. (2001) [Pubmed]
  3. Pharmacological and molecular characterization of ATP-sensitive K(+) conductances in CART and NPY/AgRP expressing neurons of the hypothalamic arcuate nucleus. van den Top, M., Lyons, D.J., Lee, K., Coderre, E., Renaud, L.P., Spanswick, D. Neuroscience (2007) [Pubmed]
  4. Physiologic requirements during rewarming: suppression of the shivering response. Rodriguez, J.L., Weissman, C., Damask, M.C., Askanazi, J., Hyman, A.I., Kinney, J.M. Crit. Care Med. (1983) [Pubmed]
  5. Cardiopulmonary functioning in adolescent patients with mild idiopathic scoliosis. DiRocco, P.J., Vaccaro, P. Archives of physical medicine and rehabilitation. (1988) [Pubmed]
  6. An in vitro validation of a commercially available metabolic cart using pediatric ventilator volumes. Webster, P.A., King, S.E., Torres, A. Pediatr. Pulmonol. (1998) [Pubmed]
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