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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Competitive Behavior

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High impact information on Competitive Behavior

  • We find that this competitive behavior correlates with, and can be corrected by, the activation of the BMP/Dpp survival signaling pathway [1].
  • (a) NADH has an apparent competitive behavior with respect to ATP and uncompetitive behavior with respect to AMP resulting in improved binding constant in the presence of AMP, and (b) the binding of the peptide is not significantly altered by NADH [2].
  • Cyclosporin A, which inhibits the megachannel, also showed a competitive behavior versus Ca2+ [3].
  • Binding results indicated that the interaction between cetirizine, its enantiomers, and histamine is compatible with a competitive behavior, in contrast with the noncompetitive profile of cetirizine and levocetirizine observed in isolated organs [4].
  • The nicotinamide derivatives 1 and 2 were inhibitors of the enzyme as determined by competitive behavior in CD38-catalyzed conversion of nicotinamide guanine dinucleotide (NGD(+)) to cyclic GDP-ribose [5].

Chemical compound and disease context of Competitive Behavior

  • Competitive behavior is observed in reconstitution reactions containing both FAD and 8-(methylsulfonyl)FAD [6].
  • Influence of organic nutrients and cocultures on the competitive behavior of 1,2-dichloroethane-degrading bacteria [7].
  • As outlined in the trade-off hypothesis of testosterone (T) secretion, fluctuations in T during the breeding season might reflect how males allocate their time and energy to competitive behaviors for mates and territories, associated with high T levels, and parental activities, associated with low T levels [8].
  • This study identifies surface chemistry characteristics based on competitive behavior in the simultaneous adsorption behavior of NOx (NO rich) and SO2 using KOH impregnated activated carbon (K-IAC) in excess O2 [9].
  • Imipramine, desipramine, amoxapine and fluoxetine, representing three different classes of antidepressant drugs, were each able to increase competitive behavior in submissive mice and to decrease the dominance level between dominant and submissive mice in the behavioral tests [10].

Biological context of Competitive Behavior


Gene context of Competitive Behavior

  • Competitive adsorption caused displacement of bound BSA monomer by the more strongly binding BSA dimer, illustrating that even apparently single-protein systems may display multicomponent competitive behavior [12].
  • The reduction od sodium appetite in female rats may have been in part due to the competitive behavior of grooming that followed the OT injection [13].


  1. dMyc transforms cells into super-competitors. Moreno, E., Basler, K. Cell (2004) [Pubmed]
  2. Biochemical regulation of mammalian AMP-activated protein kinase activity by NAD and NADH. Rafaeloff-Phail, R., Ding, L., Conner, L., Yeh, W.K., McClure, D., Guo, H., Emerson, K., Brooks, H. J. Biol. Chem. (2004) [Pubmed]
  3. Modulation of the mitochondrial megachannel by divalent cations and protons. Szabó, I., Bernardi, P., Zoratti, M. J. Biol. Chem. (1992) [Pubmed]
  4. Binding characteristics of cetirizine and levocetirizine to human H(1) histamine receptors: contribution of Lys(191) and Thr(194). Gillard, M., Van Der Perren, C., Moguilevsky, N., Massingham, R., Chatelain, P. Mol. Pharmacol. (2002) [Pubmed]
  5. Mechanism-based inhibitors of CD38: a mammalian cyclic ADP-ribose synthetase. Sauve, A.A., Schramm, V.L. Biochemistry (2002) [Pubmed]
  6. Affinity probing of flavin binding sites. 1. Covalent attachment of 8-(methylsulfonyl)FAD to pig heart lipoamide dehydrogenase. Raibekas, A.A., Jorns, M.S. Biochemistry (1994) [Pubmed]
  7. Influence of organic nutrients and cocultures on the competitive behavior of 1,2-dichloroethane-degrading bacteria. van den Wijngaard, A.J., van der Kleij, R.G., Doornweerd, R.E., Janssen, D.B. Appl. Environ. Microbiol. (1993) [Pubmed]
  8. Effects of testosterone on song, aggression, and nestling feeding behavior in male great tits, Parus major. Van Duyse, E., Pinxten, R., Eens, M. Hormones and behavior. (2002) [Pubmed]
  9. Studies on the surface chemistry based on competive adsorption of NOx-SO2 onto a KOH impregnated activated carbon in excess O2. Lee, Y.W., Park, J.W., Yun, J.H., Lee, J.H., Choi, D.K. Environ. Sci. Technol. (2002) [Pubmed]
  10. Submissive behavior in mice as a test for antidepressant drug activity. Malatynska, E., Rapp, R., Harrawood, D., Tunnicliff, G. Pharmacol. Biochem. Behav. (2005) [Pubmed]
  11. Conformations of lysine-sensitive aspartokinase. Shaw, J.F., Smith, W.G. Biochim. Biophys. Acta (1976) [Pubmed]
  12. Competitive adsorption of alpha-lactalbumin and bovine serum albumin to a sulfopropyl ion-exchange membrane. Weinbrenner, W.F., Etzel, M.R. Journal of chromatography. A. (1994) [Pubmed]
  13. Sex difference in sensitivity to exogenous oxytocin in different models of sodium appetite in the rat. Polidori, C., Venturi, F., De Caro, G. Acta bio-medica de L'Ateneo parmense : organo della Società di medicina e scienze naturali di Parma. (1994) [Pubmed]
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